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百令胶囊治疗慢性马兜铃酸肾病的临床观察
引用本文:高智,库宝庆,秦永芳,郭正东. 百令胶囊治疗慢性马兜铃酸肾病的临床观察[J]. 中国药师, 2007, 10(9): 851-853
作者姓名:高智  库宝庆  秦永芳  郭正东
作者单位:华中科技大学同济医学院附属襄樊医院中西医结合肾病科,湖北襄樊,441021
摘    要:目的:探讨百令胶囊治疗慢性马兜铃酸肾病(CAAN)的疗效。方法:治疗组15例CAAN患者,用百令胶囊治疗,治疗效果与用泼尼松治疗组(对照组)12例比较。结果:治疗组治疗后血SCr、Ccr较治疗前无明显变化(P>0.05);对照组治疗后SCr较治疗前明显升高(P<0.05);对照组Ccr低于治疗前(P<0.01)。结论:用百令胶囊能够明显延缓CAAN患者肾功能进行性减退;泼尼松不能够控制CAAN患者肾功能进行性减退。

关 键 词:慢性马兜铃酸肾病  百令胶囊  泼尼松
文章编号:1008-049X(2007)09-0851-03
修稿时间:2007-04-03

Efficacy of Corbrin Capsule in Treatment of Chronic Aristolochic Acid Nephropathy
Gao Zhi,Ku Baoqing,Qin Yongfang,Guo Zhengdong. Efficacy of Corbrin Capsule in Treatment of Chronic Aristolochic Acid Nephropathy[J]. China Pharmacist, 2007, 10(9): 851-853
Authors:Gao Zhi  Ku Baoqing  Qin Yongfang  Guo Zhengdong
Affiliation:Department of Nephrology, Xiamgfanshi Center Hospital, Hubei, Xiangfan 441021, China
Abstract:Objective:To investigate the efficacy of corbrin capsule in the treatment of chronic aristolochic acid nephropathy (CAAN).Method:The treated group was treated with corbrin capsule in 15 patients with CAAN.The therapeutic effect was compared with that of the controlled group treated with prednisone.Result:There was a notable increased of SCr and decreased of Ccr after the treatment in the prednisone group(P<0.05);but in the treated group ,there was not any notable differences of Scr before and after the treatment(P>0.05).Conclusion:Corbrin capsule can markedly retard the deterioration of renal function of the patients with CAAN,but prednisone can not.
Keywords:Chronic aristolochic acid nephropathy  Corbrin capsule  Prednisone
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