2007年广东省监狱系统HIV／AIDS患者的CD4^＋T细胞计数结果分析——附436例报告

目的：了解广东省监狱系统在押HIV／AIDS犯人的细胞免疫状况，为临床防治AIDS提供参考。方法：应用流式细胞仪对436例广东省监狱系统的在押的HIV／AIDS患者进行CD4^＋T细胞计数，并定期监测。结果与结论：436例中的感染者CD4^＋T细胞计数结果少于200／μL者占24．5％，200～350／μL者占26．6％，超过350／μL者占48．9％。不同年龄组之间CD4^＋T细胞计数存在差异，25岁以后随着年龄增长，CD4^＋T细胞计数呈下降趋势。未经治疗的201例患者3个月后CD4^＋T细胞计数较首次检测明显下降，而经治疗的20例则明显增加。提示应对HIV／AIDS患者的CD4^＋T细胞计数进行检测及定期监测，以了解其免疫状态的变化，并应予积极的抗病毒治疗以改善其免疫状况。

Analysis of CD4+ T lymphocyte counts among prisoners with HIV/AIDS in prison system of Guangdong Province during 2007

Objective： To investigate the cell immune status of prisoners with of Guangdong province for offering reference to prevention and treatment HIV/AIDS, analysis were used for CD4^＋ T lymphocyte counts in 436 prisoners with HIV/AIDS in HIV/AIDS in prison system Methods： Flow cytometry prison system of Guangdong province. Results and Conclusion： 24. 5% of 436 HIV positive prisoners had CD4^＋ T lymphocyte counts lower than 200/μL, 26. 6% from 200/μL to 349/p,L, and 48.9% more than 350/p,L. The CD4^＋ T lymphocyte count had significant difference among different age groups, and the CD4^＋T lymphocyte counts in patients over 25 years old trended to decrease with increasing age. Compared to the first test results, the CD4^＋T lymphocyte counts of 201 cases without therapy obviously decreased after 3 months, CD4^＋ T lymphocyte counts of 20 cases with therapy obviously increased inversely. It shows that CD4 ^＋ T lymphocyte counts of HIV/AIDS patients should be detected and followed periodically to comprehend the change of their immune status, and antiviral therapy should be offered energetically to improve their immune status.