| 囊性肺纤维化同种异体肺移植1例报告 |
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| 引用本文： | 陈钢,杨锡耀,蔡瑞君,黄志勇,穆峰,吴旭,孟辉.囊性肺纤维化同种异体肺移植1例报告[J].南方医科大学学报,2003,23(10):1115-1116. |
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| 作者姓名： | 陈钢 杨锡耀 蔡瑞君 黄志勇 穆峰 吴旭 孟辉 |
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| 作者单位： | 第一军医大学南方医院胸外科,广东,广州,510515 |
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| 摘 要： | 为1例17岁女性严重囊性肺纤维化患者行右侧单肺移植,术中未用体外循环,供肺采用冷UW液灌注,冷缺血时间280 min。术后18 h停用呼吸机,第4天下地活动。术后免疫抑制剂选用甲基强的松龙冲击治疗后再用“新三联”(FK 506,骁悉,强的松)维持后续治疗。患者术后恢复顺利,复查肺功能基本正常,动脉血气分析显示较术前明显改善。术后第1个月未出现严重排异反应,目前存活状况良好。
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| 关 键 词： | 肺纤维化 肺移植 |
| 文章编号： | 1000-2588(2003)10-1115-02 |
| 修稿时间： | 2003年7月25日 |
Lung transplantation for treatment of pulmonary cystic fibrosis: report of one case |
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| CHEN Gang,YANG Xi-yao,CAI Rui-jun,HUANG Zhi-yong,MU Feng,WU Xu,MENG Hui.Lung transplantation for treatment of pulmonary cystic fibrosis: report of one case[J].Journal of Southern Medical University,2003,23(10):1115-1116. |
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| Authors: | CHEN Gang YANG Xi-yao CAI Rui-jun HUANG Zhi-yong MU Feng WU Xu MENG Hui |
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| Affiliation: | CHEN Gang,YANG Xi-yao,CAI Rui-jun,HUANG Zhi-yong,MU Feng,WU Xu,MENG Hui Department of Thoracic and Cardiovascular Surgery,Nanfang Hospital,First Military Medical University,Guangzhou 510515,China |
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| Abstract: | A right single lung transplantation was performed in a 17-year-old female patient with end-stage cystoid pulmonary fibrosis and without cardiopulmonary bypass in June 2003. The donor lung was perfused with cold UW solution with a cold ischemic time of 280 min. The patient weaned from ventilator on the next day of operation (18 h later) and was able to walk at the fourth day postoperatively. Immunosuppression included methylprednisolone used before FK 506, mycophenolate mofetil and prednisone dosed after operation. The patient remains well a month after operation with significant improvement of the lung function and enjoys normal life. |
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| Keywords: | pulmonary fibrosis lung transplantation |
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