局部亚低温对重症脑梗死患者血清NSE的影响

目的 探讨局部亚低温对重症脑梗死患者血清神经元特异性烯醇化酶(NSE)水平的影响.方法 84例重症脑梗死患者分为治疗组和对照组各42 例,对照组采用常规治疗,亚低温组在此基础上进行局部亚低温治疗,两组患者均在治疗前和治疗后第3 、7、14 d测定血清NSE 水平,并在治疗后14 d进行临床疗效的判定.结果 亚低温组第7 d和第14 d的NSE明显低于对照组(P<0.05).亚低温组治疗14 d后临床疗效明显高于对照组(P<0.05) 结论亚低温治疗可降低重症脑梗死患者血清NSE 水平,改善重症脑梗死患者的预后.

The influence of using local mild hypothermia to the NSE of the blood serum of those suffering from severe cerebral infarction

Objective To discuss the influence of using local mild hypothermia to the NSE of the blood serum of those suffering from severe cerebral infarctiorn. Methods 84 patients suffering from severe cerebral infarction were equally divided into two groups. The control group of 42 were adopted routine therapy, while the other group using local mild hypotbermia as well. Both of the two groups bad been tested the level of NSE of the blood serum before the treatment and on the 3^rd, 7^th and 14^th day respectively during the treatment. Results The judgement on the clinical effect was drawn on the 14^th day. Accordingly, the NSE of the treatment group was apparently lower than the control group （P〈0. 05） on the 7^th and the 14^th day and the clinical effect better than the control group （P〈0. 05） on the 14^th day. Conclusions Mild hypotbermia can reduce the level of NSE of the blood serum of those suffering from severe cerebral infarction and improve their prognosis.