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野八角果毒性成分的研究*
引用本文:杨春澍,王嘉琳,张志亮,河野功.野八角果毒性成分的研究*[J].药学学报,1991,26(2):128-131.
作者姓名:杨春澍  王嘉琳  张志亮  河野功
作者单位:北京中医学院中药系,北京中医学院中药系,美国瓦里安公司北京仪器展示室,日本长崎大学药学部 北京 100029,北京 100029,北京 100083,长崎 852
摘    要:从野八角(Illicium simonsii Maxim.)的果实中分得三个化合物,经光谱分析并与标准品对照证明,结晶Ⅱ和Ⅲ分别为已知化合物莽草毒素(anisatin)和莽草酸(shikimic acid),另一个为新的毒性甚强的倍半萜内酯,命名为2-oxo-6-deoxyneoanisatin(Ⅰ)

关 键 词:野八角  莽草酸  莽草毒素  2-oxo-6-deoxyneoanisatin
收稿时间:1989-12-04

STUDIES ON THE TOXIC CONSTITUENTS OF ILLICIUM SIMONSII MAXIM.
CS Yang,JL Wang,ZL Zhang,and I Kouno.STUDIES ON THE TOXIC CONSTITUENTS OF ILLICIUM SIMONSII MAXIM.[J].Acta Pharmaceutica Sinica,1991,26(2):128-131.
Authors:CS Yang  JL Wang  ZL Zhang  and I Kouno
Affiliation:Faculty of Chinese Pharmacy, Beijing College of Traditional Chinese Medicine.
Abstract:A new sesquiterpenelactone compound was isolated along with the known anisatin and shikimic acid from pericarps of the fruit of Illicium simonsii Maxim., family Magnoliaceae, collected in Sichuan province. This new sesquiterpene lactone compound exhibited high toxicity in mice. The structure of which was elucidated as 2-oxo-6-deoxyneoanisatin (I) based on spectral evidences. The detailed physical and chemical data were presented.
Keywords:Illicium simonsii Maxim    Shikimic acid  Anisatin  2-oxo-6-deoxyneoanisatin
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