儿童传染性单核细胞增多症临床特征分析

目的探讨儿童传染性单核细胞增多症（IM）的临床特点。方法回顾性分析2005年8月-2009年8月收治的151例IM患儿的症状、体征、实验室检查及治疗效果。结果 IM临床表现以发热、咽峡炎、肝脾和淋巴结肿大最常见,鼻塞、眼睑浮肿也是重要体征。外周血出现异型淋巴细胞及EBV-IgM抗体检测可帮助确诊。更昔洛韦治疗IM效果确切。结论应重视IM临床特点,有助于早期诊断并提高确诊率,应用更昔洛韦治疗值得推广。

Analysis on Clinical Characteristics of Infectious Mononucleosis in Children

Objective To investigate the clinical features of infectious mononucleosis （IM） in children.Methods A total of 151 children with infectious mononucleosis admitted from August 2005 to August 2009 were reviewed.The symptoms,signs,laboratory tests,and treatment of infectious mononucleosis were analyzed.Results Fever,angina, hepatomegaly,splenomegaly,and swollen lymph nodes were the most common clinical manifestations of IM.Nasal congestion and eyelid edema were also two important signs.Atypical lymphocytes in peripheral blood and EBV antibody （VCA-IgM） could help confirm the diagnosis.The antiviral treatment with ganciclovir was effective for infectious mononucleosis.Conclusion Clinical features of infectious mononucleosis are helpful to the diagnosis.Treatment with ganciclovir should be promoted.