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质谱新技术在毒品分析中的应用
引用本文:贾滨,;徐国宾,;吕小宝,;张玉荣,;杨芃原.质谱新技术在毒品分析中的应用[J].生命科学仪器,2014(4):7-10.
作者姓名:贾滨  ;徐国宾  ;吕小宝  ;张玉荣  ;杨芃原
作者单位:[1]复旦大学化学系,复旦大学生物医学研究院,上海200433; [2]上海市公安局物证鉴定中心,上海200083
基金项目:国家自然科学基金863项目(2012AA020202); 国家自然科学基金(21227805)资助; 973项目(2010CB912700,2012CB910600,2013CB911201)
摘    要:毒品分析是办理涉毒犯罪案件的重要环节之一,为案件侦破和证据收集提供重要依据。质谱分析法具有灵敏度高、分析速度快、所需样品量少等特点,因其出色的分析性能越来越受到分析人员的重视。本文综述了色谱质谱联用技术和新兴原位直接电离质谱技术在毒品分析领域的应用情况,并展望了质谱新技术在毒品分析领域的发展前景。

关 键 词:毒品分析  质谱  气相色谱质谱联用  液相色谱质谱联用  原位直接电离

Applications of New Mass Spectrometry Techniques in Analyzing Illicit Drugs
Affiliation:Jia Bin, Xu Guobin, Lu Xiaobao, Zhang Yurong, Yang Pengyuan (1. Department of Chemistry and Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai 200433, P R. China; 2. Shanghai Institute of Forensic Science, Shanghai, 200083, P R. China)
Abstract:The analysis of illicit drugs is one of the important link of handling the drug-related crimes, providing the important basis for the criminal investigation and evidence collection. Mass spectrometry has the advantages of high sensitivity, fast analysis speed and needing little sample quantity. Due to its excellent performance, mass spectrometry analysis has attracted more and more attention. This paper reviews the applications of GC/MS, LC/MS and ambient ionization(AI) mass spectrometry in the analysis of illicit drugs. What's more, the prospects and development of new mass spectrometry techniques in the fi eld of drug analysis are also discussed.
Keywords:Illicit drugs  mass spectrometry  GC/MS  LC/MS  ambient ionization
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