| 昆布多糖和猴头多糖对实验性高血糖的防治作用 |
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| 引用本文： | 薛惟建,杨文.昆布多糖和猴头多糖对实验性高血糖的防治作用[J].中国药科大学学报,1989,20(6):378-380. |
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| 作者姓名： | 薛惟建 杨文 |
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| 作者单位： | 中国药科大学生物化学研究室
(薛惟建，杨文)，中国药科大学生物化学研究室(陈琼华) |
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| 摘 要： | 糖尿病患病率和死亡率逐年增高,高血糖还可诱发冠心病和动脉粥样硬化,它已严重地危害了人们的生命健康。本文探讨了猴头多糖(Hericium erinacaus Polysaccharide,简称HP),褐藻淀粉(Laminarin,LA)和褐藻酸钠(Sodium alginate,SA)对实验性高血糖的防治作用。
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| 关 键 词： | 猴头多糖 褐藻酸钠 褐藻淀粉 糖尿病 降血糖 |
PREVENTION AND TREATMENT OF ALLOXAN-INDUCED DIABETES IN MICE BY THE POLYSACCHAREDES FROM LAMINARIA JAPONICA AND HERICIUM ERINACAUS |
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| Xue Weijian,Yang Weng Chen Qionghua Division of Biochemistry.PREVENTION AND TREATMENT OF ALLOXAN-INDUCED DIABETES IN MICE BY THE POLYSACCHAREDES FROM LAMINARIA JAPONICA AND HERICIUM ERINACAUS[J].Journal of China Pharmaceutical University,1989,20(6):378-380. |
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| Authors: | Xue Weijian Yang Weng Chen Qionghua Division of Biochemistry |
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| Abstract: | Hericium erinaeaus polysaccharide (HP) ig 25mg/kg, Laminarin (LA) ig 100mg/kg and Sodium alginate (SA) ip 300mg/kg reduced the blood glucose level in normal mice by 53%, 49% and 38% respectively at 7 hours after administration. HP (ig 25mg/kg), LA (ig 300 rag/kg) and SA (ip 300mg/kg) were able to lower blood glucose level by 50%, 61% and 39% respectively at 24 hours after administration in alloxan-induced diabctic mice. Three polysaccharidcs also exhibited preventable effects on alloxan-induced diabetic mice. The results showed that HP had the Strongest hypoglycemic action, LA moderate effect and SA only weak effect. |
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| Keywords: | Hericium erinacaus polysaccharide Sodium alginate Laminarin Diabetes Hypoglycemic action |
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