| 2019冠状病毒病相关肾损伤研究进展 |
| |
| 引用本文： | 周加军,余永武,张凌.2019冠状病毒病相关肾损伤研究进展[J].中南大学学报(医学版),2021,45(10):1241-1246. |
| |
| 作者姓名： | 周加军 余永武 张凌 |
| |
| 作者单位： | 1. 皖南医学院第一附属医院血液净化中心，安徽芜湖241000；2. 清华大学附属垂杨柳医院，北京100022；
3. 中日友好医院肾内科，北京100029 |
| |
| 基金项目： | 吴阶平医学基金(320.6750.18110)；芜湖市科技民生专项基金(2020ms3-6)；皖南医学院弋矶山医院引进人才项目(YR201921)。 |
| |
| 摘 要： | 2019 冠状病毒病(coronavirus disease 2019，COVID-19)目前已在世界范围内暴发流行，是世界性的重大
公共卫生问题。严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2，SARS-CoV-2)传染性
极强，主要侵袭患者的肺，导致呼吸窘迫综合征甚至多器官衰竭。肾也是病毒攻击的主要器官之一，病毒通过血管
紧张素转换酶2(ACE2)直接损伤肾小管，并引起细胞因子风暴导致肾损伤，增加患者的死亡风险。早期排查COVID-
19患者肾损伤危险因素，检测肾损伤指标，对存在肾损伤的患者及时进行支持治疗及肾脏替代治疗，可降低病死率。
|
| 关 键 词： | 2019冠状病毒病 肾损伤 细胞因子风暴 血管紧张素转换酶2 |
Progress in the study on COVID-19-related renal injury |
| |
| ZHOU Jiajun,YU Yongwu,ZHANG Ling.Progress in the study on COVID-19-related renal injury[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2021,45(10):1241-1246. |
| |
| Authors: | ZHOU Jiajun YU Yongwu ZHANG Ling |
| |
| Affiliation: | 1. Blood Purification Center, First Affiliated Hospital, Wannan Medical College, Wuhu Anhui 241000;
2. Chui Yangliu Hospital Affiliated to Tsinghua University, Beijing 100022; 3. Department of Nephrology, China-
Japan Friendship Hospital, Beijing 100029, China |
| |
| Abstract: | Coronavirus disease 2019 (COVID-19) is now a major public health problem worldwide.
Infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is extremely
strong. The one major target of the virus is the lung, which leads to the deaths of respiratory
distress syndrome and multiple organ failure. The kidney is also one of the main organs
attacked by viruses, which directly damage the renal tubules through angiotensin
converting enzyme-2 and cause cytokine storm, resulting in kidney damage and increasing
the risk of death in the patients. Early investigation of risk factors for kidney injury,
detection of kidney injury indicators, timely supporting treatment and renal replacement
therapy for the existence of kidney injury patients are useful for reducing the mortality rate
of COVID-19 patients. |
| |
| Keywords: | coronavirus disease 2019 kidney injury cytokine storm angiotensin converting enzyme 2 |
|
| 点击此处可从《中南大学学报(医学版)》浏览原始摘要信息 |
|
点击此处可从《中南大学学报(医学版)》下载全文 |
