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菊花解热、降压作用的物质基础研究
引用本文:戴敏,刘青云,李道中,刘丽.菊花解热、降压作用的物质基础研究[J].中药材,2001,24(7):505-506.
作者姓名:戴敏  刘青云  李道中  刘丽
作者单位:安徽中医学院,
基金项目:本课题为国家"九五”重点科技项目(攻关)课题(№.96-903-
摘    要:目的:探讨菊花解热、降压作用的物质基础。方法:采用大鼠肛温表测定体温、大鼠颈动脉插管法测定血压值。结果:菊花挥发油(0.8ml/Kg)灌胃给药对2,4-二硝基苯酚致热大鼠体温有明显降温效应;总黄酮(57mg/kg)静脉给药对大鼠血压值有显著降低作用。结论:菊花挥发油解热、总黄酮降压是其散风清热、平肝明目的药理学基础之一。

关 键 词:菊花  挥发油  总黄酮  解热  降压
修稿时间:2001年4月17日

Research of Material Bases on Antifebrile and Hypotensive Effects of Flos Chrysanthemi
Dai Min,Liu Qingyun,Li Daozhong,Liu Li.Research of Material Bases on Antifebrile and Hypotensive Effects of Flos Chrysanthemi[J].Jorunal of Chinese Medicinal Materials,2001,24(7):505-506.
Authors:Dai Min  Liu Qingyun  Li Daozhong  Liu Li
Affiliation:Anhui College of Traditional Chinese Medicine, Hefei 230031.
Abstract:Objective: To study material bases on the antifebirle and hypotensive effect of Flos Chrysanthemi. Methods: Temperature and blood pressure of rats were measured after treatment by taking several kinds of extracts of Flos Chrysanthemi. Results: After volatile oil of Flos Chrysanthemi (0.8 ml/Kg) was taken by oral administration, temperature on the fever heat of rats could be decreased distinctly. After total flavonid of Flos Chrysanthemi (57 mg/Kg) was injected, blood pressure on rats could be reduced remarkly. Conclusion: Volatile oil of Flos Chrysanthemi has antifebrile effect and total flavonid of Flos Chrysanthemi has hypotensive effect, which are one of the Pharmacological bases of dispelling the wind-evil, clearing away the heat-evil, calming the liver, sharping eyes of Flos Chrysanthemi.
Keywords:Flos Chlyanthemi  Volatile oil  Total flavonid  Antifebrile  Hypotensive  
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