检验与病理临床分离的5932株病原菌分布及药敏分析

目的:了解临床细菌的分布情况及其药敏结果,对临床合理应用抗菌药物提供帮助。方法:对临床送检的标本进行分离培养,对阳性标本进行药敏试验。结果:培养出病原菌5 932株,其中阴性杆菌与阳性球菌分别为61.4%和38.6%。阴性杆菌对碳青酶烯类、头孢哌酮钠-舒巴坦、哌拉西林钠-他唑巴坦、阿米卡星等抗菌药物较为敏感,阳性球菌对万古霉素、替考拉宁、呋喃妥因、利福平较为敏感。结论:医院细菌感染以阴性杆菌为主,门诊标本分离以阳性球菌为多。细菌耐药性较强,耐药率较高,值得临床关注和进一步研究。

Distribution and Drug Sensitivity of Bacteria Separated from 5932 Clinical Cases

Objective:To investigate the bacteria distribution and drug sensitivity of bacteria separated in our hospital clinical bacteria laboratory in 2006 and provide help to rational application of clinical antibacterial drugs.Methods:The samples from clinical departments were separated and cultured,and drugs sensitivity tests were made in the positive samples.Results:5 932 strains of bacteria were found with 61.4% being the negative bacilli and 38.6% being positive coccobacteria.Negative bacilli are sensitive to Carbapenems,Cefoperazone-Sulbactam,Piperacillin-Tazobactam and Amikacin,while positive coccobacteria are sensitive to Vancomycin,Teicoplanin,Nitrofurantoin and Lifampin.Conclusion:The main bacteria of nosocomial infection is negative bacilli,however,in Out-Patient department the main bacteria is positive coccobacteria.The drug resistance is relatively strong,which should be paid more attention and subjected to further study.