母猪生殖器官大小和产仔数的分子遗传基础

采用单核苷酸多态分析技术（SNP）分析母猪3个生殖激素受体基因（ESR、PRLR和FSHR）的变异，屠宰103头母猪并测定其生殖器官大小；统计母猪的产仔数；利用SAS或SPSS分析软件分析基因变异与母猪的生殖器官大小，产仔数多少的连锁关系，以探讨母猪生殖器官大小和产仔数多少的分子遗传基础，结果表明，如母猪携带的基因型为位点，ESR的BB型，位点FSHRB的BB型，位点ESRB的AA型，位点PRLR的AA型，则母猪的生殖器官较大，产仔数也较多；在位点ESRB或位点PRLR中，带有AA基因型母猪不仅产仔数显著地高于AB、BB型，而且生殖器官也显著大于AB、BB型；在位点ESR和FSHRB中，带有BB基因型母猪的生殖器官，产仔数显著高于带有AB或AA型母猪。

Study of Molecular Genetics of the Size of Reproductive Organs and Litter Size in the Sow

The mutations of ESR?PRLR and FSHR genes were investigated by SNP;103 F 2 sows were slaughtered and their reproductive organs were determined;the litter size of sow was recorded. The linkage between mutations of genes and size of reproductive organ?litter size was analyzed. The results revealed:these sows that could provide more piglets with bigger reproductive organs usually carried genotype like as genotype BB on the sites of ESR?FSHRB and the genotype AA on the sites of ESRB and PRLR ,that is,the genotype of BB on the sites of ESR or FSHRB in sow was not only helpful to promote growth of reproductive organs,but also benefit to improve litter size;The size of productive organs and litter size of the sow with genotype AA on the sites of ESRB or PRLR were significantly higher than those of sow with genotype AB or BB .