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宫颈癌患者CD58/CD2的表达及临床意义
引用本文:张婷,王俊峰,许婷姝,吕晓婷,许飞.宫颈癌患者CD58/CD2的表达及临床意义[J].中国妇幼保健,2011,26(2):268-269.
作者姓名:张婷  王俊峰  许婷姝  吕晓婷  许飞
作者单位:南京医科大学附属无锡妇幼保健院遗传实验室,214002
基金项目:无锡市科技局科研项目,南京医科大学科技发展基金面上项目
摘    要:目的:探讨CD58/CD2在宫颈癌患者的表达水平及临床意义。方法:分别应用免疫组织化学技术及流式细胞术检测40例宫颈癌患者及30例C IN患者组织CD58水平和外周血CD2+细胞百分率,以30例子宫肌瘤患者作为正常对照。结果:宫颈癌患者外周血CD2+细胞百分率及癌组织CD58表达水平均明显低于C IN组及正常对照组,差异均具有统计学意义(P<0.05)。结论:CD58/CD2的表达与宫颈癌的发生、发展有关,二者可作为治疗及评价预后的参考指标。

关 键 词:宫颈癌  CD58  CD2  免疫组织化学  流式细胞术

Expression of CD58/CD2 in patients with uterine cervix cancer and its clinical significance
ZHANG Ting,WANG Jun-Feng,XU Ting-Zhu,et al..Expression of CD58/CD2 in patients with uterine cervix cancer and its clinical significance[J].Maternal and Child Health Care of China,2011,26(2):268-269.
Authors:ZHANG Ting  WANG Jun-Feng  XU Ting-Zhu  
Affiliation:ZHANG Ting,WANG Jun-Feng,XU Ting-Zhu,et al.Maternity and Children Health Care Hospital of Wuxi,Nanjing Medical University,Wuxi 214002,Jiangsu,China
Abstract:Objective:To explore the expression level of CD58/CD2 and its clinical significance in patients with uterine cervix cancer.Methods:Immunohistochemistry method was used to detect the expression of CD58 and flow cytometry was used to detect the CD2 expression in 40 patients with uterine cervix cancer and 30 CIN patients,30 cases of hysteromyoma were collected as normal controls.Results:The expression of CD2 and CD58 in patients with uterine cervix cancer were significantly lower than those in CIN patients and...
Keywords:CD58  CD2
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