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64层螺旋CT重建层厚及重建间距与CAD肺结节检出准确性的关系分析
引用本文:齐敏,雷晓燕,黄明刚,张小玲,吴晓红,郭佑民.64层螺旋CT重建层厚及重建间距与CAD肺结节检出准确性的关系分析[J].第四军医大学学报,2009,30(10):932-935.
作者姓名:齐敏  雷晓燕  黄明刚  张小玲  吴晓红  郭佑民
作者单位:齐敏,QI Min(西安交通大学医学院第二附属医院影像中心,陕西,西安,710004;陕西省人民医院影像中心,陕西,西安,710068);雷晓燕,黄明刚,张小玲,吴晓红,LEI Xiao-Yan,HUANG Ming-Gang,ZHANG Xiao-Ling,WU Xiao-Hong(陕西省人民医院影像中心,陕西,西安,710068);郭佑民,GUO You-Min(西安交通大学医学院第二附属医院影像中心,陕西,西安,710004)  
基金项目:陕西省科学技术研究发展计划 
摘    要:目的:评估不同重建层厚及重建间距对Lung Care软件CAD系统检出肺结节准确性的影响.方法:纳入48例肺结节患者,每位患者重建5组数据,层厚/间距分别为:0.75/0.70mm,1/1mm,3/3mm,5/1mm,5/5mm.利用ROC曲线对比不同重建参数时CAD的检测准确性.结果:根据参考标准共检出152个肺结节.在0.75,1mm层厚时的曲线下面积(Az)值(分别为0.86,0.84)均显著高于3,5mm层厚时(3/3,5/1,5/5mm时Az值分别为0.48,0.53,0.40)(P〈0.05);重叠重建(5/1mm)时,CAD检出肺结节的Az值(Az=0.53)大于5mm层距时(Az=0.40),二者无显著性差异,但明显低于1mm层厚重建(Az=0.84,P〈0.05).1mm层厚重建时CAD检出肺结节的灵敏度最高(84%);0.75mm层厚重建时平均每位患者的假阳性数最低(0.56).随层厚增加,CAD检出肺结节的平均直径逐渐增大,检出小结节的数目明显下降.结论:使用薄层重建(层厚0.75mm或1mm)图像时,CAD的检出准确性显著高于厚层重建(层厚3mm或5mm)时.重叠重建(5/1mm)可以提高CAD的准确性,但其作用非常有限.

关 键 词:计算机辅助检测  肺结节  体层摄影术  螺旋计算机  图像重建

Relationship of reconstruction slice thickness and interval with accuray of computer-aided detection system:detection of pulmonary nodules by 64-slice helical CT
QI Min,LEI Xiao-Yan,HUANG Ming-Gang,ZHANG Xiao-Ling,WU Xiao-Hong,GUO You-MinImaging Center,Second Affiliated Hospital,Medical School of Xi''an Jiaotong University,Xi''an ,China,Imaging Center,Shaanxi Province People''s Hospital,Xi''an.Relationship of reconstruction slice thickness and interval with accuray of computer-aided detection system:detection of pulmonary nodules by 64-slice helical CT[J].Journal of the Fourth Military Medical University,2009,30(10):932-935.
Authors:QI Min  LEI Xiao-Yan  HUANG Ming-Gang  ZHANG Xiao-Ling  WU Xiao-Hong  GUO You-MinImaging Center  Second Affiliated Hospital  Medical School of Xi'an Jiaotong University  Xi'an  China  Imaging Center  Shaanxi Province People's Hospital  Xi'an
Affiliation:QI Min1,2,LEI Xiao-Yan2,HUANG Ming-Gang2,ZHANG Xiao-Ling2,WU Xiao-Hong2,GUO You-Min11Imaging Center,Second Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710004,China,2Imaging Center,Shaanxi Province People's Hospital,Xi'an 710068
Abstract:AIM:To evaluate the effect of various reconstruction slice thicknesses and reconstruction intervals on diagnostic accuracy of pulmonary nodules with the computer-aided detection (CAD) system of LungCare software. METHODS:Forty-eight patients with pulmonary nodules, five sets of CT images were reconstructed in each patient by selecting five reconstruction slice thickness and interval combinations respectively: 0.75/0.70 mm, 1/1 mm,3/3 mm, 5/1 mm, 5/5 mm.The performance of the CAD system using different recon...
Keywords:computer-assisted detection  lung nodules  tomography  spiral computed  image reconstruction  
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