重型肝炎继发细菌感染的预后分析

目的 :为了探讨重型肝炎继发细菌感染对其预后的影响。方法 :对 6 0例重型肝炎进行回顾性分析 ,并对感染的部位及感染率进行统计。结果 :重型肝炎合并细菌感染 33例 ,其感染率 5 5 %。感染部位最多是腹腔 2 4例(72 .7% ) ,其次是胆道 17例 (5 7.6 % ) ,呼吸道 11例 (33.3% ) ,肠道 7例 (2 1% ) ,尿道 3例 (9.1% ) ,心包和皮肤感染各1例 (3% )。一个患者感染部位最少的是 1个 ,最多的是 5个。非感染组和感染组早、中、晚期好转率分别为 88.2 3% ,80 % ,2 5 %和 5 0 % ,5 0 % ,16 .6 % (P <0 .0 5 )。结论 :早期发现重型肝炎继发细菌感染 ,及时选用有效抗生素是抢救重症肝炎的重要措施之一。

Analysis of prognosis caused by secondary bacterial infection in severe viral hepatitis

Objective To explore the prognosis caused by secondary bacterial infection in severe viral hepatitis. Methods We analysed 60 cases of severe viral hepatitis retrospectively and assayed the infection sites and rates. Results Of the 60 patients, 33 were associated with bacterial infection with an infection rate of 55%. The abdomen was the most commonly infected site, and 24 such cases of infection accounted for 72.7% of the overall infection rate, which was followed by the biliary tract (17/57.6%), respiratory tract (11/33.3%), intestinal tract (7/21%), urinary tract (3/9.1%), pericardial infection (1/3%) and skin infection (1/3%). The number of infected sites in the patients ranged from 1 to 5. For the non infection group, the effect rates of the early stage, middle stage and late stage were 88.2%, 88% and 25% respectively while the rates of the infection group were 50%, 50% and 16.6% respectively. There was a significant difference between the two groups, especially in the early stage (P<0.05). Conclusion It is one of the important therapies to identify secondary bacterial infection in severe viral hepatitis as early as possible and select effective antibiotics promptly.