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Polylactide and polyglycolic acid-reinforced coralline hydroxy-apatite for the reconstruction of cranial bone defects in the rabbit |
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| Authors: | T Antikainen M Ruuskanen R Taurio M Kallioinen W Serlo P Törmälä T Waris |
| Affiliation: | (1) Department of Surgery, Oulu University Central Hospital, Finland;(2) Department of Pathology, Oulu University Central Hospital, Finland;(3) Department of Paediatric Surgery of the Oulu University Central Hospital, Finland;(4) Division of Plastic Surgery of the Helsinki University Central Hospital, Finland;(5) Biomaterials Laboratory, Finland;(6) Institute of Plasties Technology of the University of Tampere, Finland |
| Abstract: | Summary The possibility of using coralline hydroxy-apatite in combination with polylactide and polyglcycolic acid instead of a bone graft in the skull region is examinated. Coralline hydroxy-apatite blocks strengthened with a membrane made of a combination of polylactide and polyglycolic acid were inserted into bony defects created in 12 rabbit skulls. The blocks were observed during a follow-up of 12 months. They became fixed to the surrounding bone and no adverse effects or harmful reactions in the nearby tissues could be detected. |
| Keywords: | Cranioplasty skull defect hydroxy-apatite bone defect |
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