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肝细胞癌病人自身抗体的检测分析
引用本文:孙明祥,胡琏,刘爱艳,蔡访勤.肝细胞癌病人自身抗体的检测分析[J].肿瘤基础与临床,1992(3).
作者姓名:孙明祥  胡琏  刘爱艳  蔡访勤
作者单位:解放军153医院,解放军153医院,解放军153医院,河南省医学科学研究所 研究员
摘    要:用间接免疫荧光法检测了资料较全的77例肝细胞癌病人血清中的三种自身抗体:抗核抗体(ANA)、抗平滑肌抗体(SMA)和抗线粒体抗体(AMA)。发现不论是在Ⅰ期、Ⅱ期和Ⅲ的肝细胞癌病人ANA和SMA均明显增高;而肝硬化病人的AMA高于肝细胞癌患者,这对于指导临床诊断和治疗以及预后判断有一定的参考价值。

关 键 词:肝细胞癌  自身抗体  免疫荧光

Detection and Analysis of the Autoantibodies of the Patients with Hepatoceilular Carcinoma
Sun Mingxiang,et al The th PLA Hospital,Zhengzhou.Detection and Analysis of the Autoantibodies of the Patients with Hepatoceilular Carcinoma[J].journal of basic and clinical oncology,1992(3).
Authors:Sun Mingxiang  The th PLA Hospital  Zhengzhou
Affiliation:Sun Mingxiang,et al The 153th PLA Hospital,Zhengzhou,450065
Abstract:Seventy seven cases of hepatocellular carcinoma with more comprehensive data in our hospital were selected to be detected their autoantibodies, among thich the antinuclear antibody(ANA), the smooth muscle autibody(SMA)and the antimitochondrial antibody(AMA) were mainly detected. It was found that both ANA and SMA in the blood serum of the patients with hepatocellular carcinoma was obviously increased no matter whether the patients was in the first,second or third stage of hepatocellular carcinoma while the AMA in patients with cirrhosis was far higher than that of patients with hepatocellular carcinoma. The result is of great importance in guiding clinical diagnosis and trestment, and helping doctors observe the therapeutic effectiveness and estimate prognosis.
Keywords:hepatocellular carcinoma  autoantibody  immunofluorescence
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