空腹血糖、餐后2h血糖、糖化血红蛋白检测在糖尿病诊断中的临床价值分析

目的 探讨空腹血糖（FPG）、餐后2h血糖（2hPG）、糖化血红蛋白（HbA1c）检测在糖尿病诊断中的临床价值。方法 对198例2型糖尿病确诊者（2型糖尿病组）、110例空腹血糖受损者（空腹血糖受损组）及118例健康者（正常对照组）进行FPG、2hPG及HbA1c测定，对检测结果 进行计量资料统计学分析和各项诊断指标诊断糖尿病的确诊率及漏诊率分析。结果 2型糖尿病组的FPG、2hPG、HbA1c明显高于正常对照组，差异有统计学意义（则5）。空腹血糖受损组的FPG和HbA1c明显高于正常对照组，差异有统计学意义（P〈0．05），2hPG与正常对照组比较。差异无统计学意义（P〉0．05）。198例糖尿病患者中FPG确诊率为48．0％，2hPG确诊率为91．4％，HbA1c确诊率为89．9％，三者联合检测确诊率为98．5％，明显高于任一单项指标的确诊率，差异有统计学意义（P〈0．05）。结论 FPG、2hPG及HbA1c作为糖尿病诊断指标，有其自身的诊断特点，联合检测能进一步提高糖尿病的检出率．在糖尿病的筛查、诊断和风险评估上具有重要的临床意义和价值。

Analysis of the clinical value on fasting plasma glucose,2 h postprandial plasma glucose and glycosylated hemoglobin in the diagnostic of diabetes mellitus

Objective To observe the clinical value of fasting plasma glucose （FPG）,2 h postprandial plasma glucose （2hPG） and glycosylated hemoglobin （HbA1c） in the diagnostic of diabetes mellitus.Methods The FPG,2hPG and HbAlc of 198 cases of patients with type 2 diabetes mellitus,110 cases of patients with impaired fasting plasma glucose and 118 cases of healthy people was tested.The test outcomes and the positive rate and misdiagnosed rate of diabetes mellitus was analyzed.Results The FPG,2hPG and HbAlc in the group of type 2 diabetes mellitus was higher than that of the group of healthy people respectively,the difference was significant （P〈0.05）.The FPG and HbAlc in the group of impaired fasting plasma was obviously higher than that of the group of healthy people,the difference was significant （P〈 0.05）;but the 2hPG had no significant difference （P〉0.05）.The diagnosis rate of the FPG in the group of 198 cases of patients with diabetes mellitus was 48.0%,the diagnosis rate of 2hPG was 91.4%,the diagnosis rate of HbAlc was 89.9%,and the diagnosis rate of all the three was 98.5%,which was evidently higher than any single index,the difference was significant （P〈0.05）.Conclusion As diagnosis index of diabetes mellitus,FPG,2hPG and HbAlc all have their own characteristics and the combined detection of the three can further enhance the prevalence of diabetes mellitus,which has major clinical significance and value in screening,diagnosing and assessing toward diabetes mellitus.