基于EQ-5D-3L和ICECAP-A量表的我国普通人群生命质量研究

目的:分析EQ-5D-3L和ICECAP-A量表评价我国普通人群生命质量的差异以及对干预方案价值评价的影响,为研究者选择合适的生命质量测量工具提供参考。方法:采用配额抽样选取802名受访者进行生命质量评价,并分别采用因子分析、多分格相关性和Bland-Altman plot一致性分析等方法探讨两量表测量结果的差异。结果:Wilcoxon秩和检验表明EQ-5D-3L量表的健康效用均值高于ICECAP-A量表的测量结果;ICECAP-A量表五个维度均主要加载于反映社会心理健康的因子1,而EQ-5D-3L量表的大部分维度主要加载于反映生理健康的因子2。部分维度之间也存在显著的相关性,但均较弱。两量表效用值的ICC为0.32,一致性分析显示5.74%的受访者超出了95%的一致性界限。结论:前者的测量内涵是健康相关生命质量,而后者则反映的是幸福感、可行能力等更广义的生命质量,其对于旨在提升公众广义幸福感和社会福祉的干预措施效果评估方面具有较好的适用性。研究者可根据测量目的及量表属性选择合适的量表,鉴于两个量表在测量内涵中的互补性,也可以在研究中同时采用两种量表以便更全面地反映干预措施的效果或受访者的生命质量。

Comparative Analysis on the Difference of EQ-5D-3L and ICECAP-A in Measuring Life Quality in China

Objective:To analyze the differences between EQ-5D-3L and ICECAP-A in evaluating the quality of life of the general population in China and their influences on the evaluation of the value of the intervention program,so as to provide references for researchers to choose the appropriate quality of life measurement tools.Methods:Quota sampling is used to select 802 interviewees for quality of life evaluation.Factor analysis,polychoric correlation analysis and Bland-Altman plot consistency analysis are used to explore the differences in the measured results of the two scales.Results:Wilcox on rank sum test shows that the mean health utility value of EQ-5D-3L is higher than that of ICECAP-A,and the difference is statistically significant.The result of factor analysis shows that the 5 dimensions of ICECAP-A are mainly loaded with factor 1 reflecting social psychological health,while most dimensions of EQ-5D-3L are mainly loaded with factor 2 reflecting physical health.The 5 dimensions of ICECAP-A are mainly loaded with factor 1 reflecting social psychological health,while most dimensions of EQ-5D-3L are mainly loaded with factor 2 reflecting physical health.The utility values of the two scales show statistically significant positive correlation,and there are also significant correlations among some dimensions,but both of them are weak.ICC of the utility values of the two scales was 0.32,and consistency plot analysis showed that 5.74%of the respondents exceeds the 95%consistency threshold.Conclusion:The measuring connotation of EQ-5D-3L is health-related quality of life,while the ICECAP-A reflects the life quality in a broader sense,such as well-being and feasible ability.The ICECAP-A is suitable for evaluating the effect of interventions aimed at improving the general well-being of the public and social well-being.Researchers can choose the appropriate scale according to the purpose of measurement and the attributes of the scale.In view of the complementarily of the two scales in the measurement connotation,they can also adopt two scales in the study to reflect the effect of intervention measures or the quality of life of interviewees more comprehensively.