| 阿昔洛韦联合胸腺肽抗乙肝病毒疗效观察 |
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| 引用本文： | 梅小平,熊良仕,李建,常茂华.阿昔洛韦联合胸腺肽抗乙肝病毒疗效观察[J].川北医学院学报,1998(4). |
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| 作者姓名： | 梅小平 熊良仕 李建 常茂华 |
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| 作者单位： | 川北医学院附院传染科 |
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| 摘 要： | 本文报道了阿昔洛韦联合胸腺肽对慢性乙型肝炎抗病毒疗效，阿昔洛韦１０ｇ，胸腺肽１６ｍｇ静滴，每日一次，连续治疗２月，共治疗３３例，治疗结束后，治疗组ＨＢｅＡｇ阴转１６例，阴转率５５１７％，ＨＢＶ ＤＮＡ阴转１８例，阴转率５４５４％。对照组ＨＢｅＡｇ阴转率９５２％（２／２５），ＨＢＶ ＤＶＡ阴转率９０９％（１／２５），两组比较有显著性差异（ｐ＜００１），表明阿昔洛韦联合胸腺肽是一种有效、价廉、使用方便的抗乙型肝炎病毒药物。
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| 关 键 词： | 阿昔洛韦 胸腺肽 抗乙肝病毒疗效 |
Observation Effect of Acyclovir and Thymetide on antiHBv in Patients of Chronic Hepatitis B |
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| Mei Xiaoping,Xiong Liangshi,Li Jian,Shang Monghua.Observation Effect of Acyclovir and Thymetide on antiHBv in Patients of Chronic Hepatitis B[J].Journal of North Sichuan Medical College,1998(4). |
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| Authors: | Mei Xiaoping Xiong Liangshi Li Jian Shang Monghua |
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| Affiliation: | Affiliated Hospital North Sichuan Medical College 637000 |
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| Abstract: | The effects of Acyclovir and Thrmetide for antiHBV in patients with chronic hepatitis B were reported. The dosage one gram of Acyclovir and Sixteen microgram of Thymetide were injected by day for 2 month. Thirty three patients with chronic hepatitis B were administrated. At the termination of therapy. sixteen cases with HBeAg positive have been seroconversed. the negative rates for HBeAg 55.17%(16/29) and 18 cases were seronepative for HBV DNA, the HBV DNA neqotive rates were 54.54%(18/33)while in control group the negative rates for HBeAg and HBV DNA were 9.52% and 9.09%. They had obvious statistical significance(P<0 01). These results suggested that Acyclovir and Thymetide was an effective、cheap and easly used anti HBV drug. |
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| Keywords: | Acyclovir Thymetide Anti HBV therapy |
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