| 复方铋合剂的制备及质量控制 |
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| 引用本文： | 王兰,左六一,雷自强,朱治本. 复方铋合剂的制备及质量控制[J]. 检验医学与临床, 2006, 3(9): 431-432 |
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| 作者姓名： | 王兰 左六一 雷自强 朱治本 |
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| 作者单位： | 重庆医科大学附属第一医院药剂科,400016 |
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| 摘 要： | 目的 制备复方铋合剂(MBC)并建立其质量控制方法 .方法 以枸橼酸铋铵为主药与氯化钾、甘油、陈皮酊等配成复方铋合剂,采用络合滴定法检测本品中铋的含量,并对制剂的稳定性进行了观察.结果 复方铋合剂的制备工艺简单,质量稳定,含量测定快速、准确.结论 该制剂工艺可用于常规制备复方铋合剂.
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| 关 键 词： | 复方铋合剂 枸椽酸铋铵 制备 质量控制 |
| 文章编号： | 1672-9455(2006)09-431-02 |
| 修稿时间： | 2006-07-03 |
Preparation and quality control of mixture bismuth composition |
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| WANG Lan,ZUO Liu-yi,LEI Zi-qiang,et al.. Preparation and quality control of mixture bismuth composition[J]. Laboratory Medicine and Clinic, 2006, 3(9): 431-432 |
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| Authors: | WANG Lan ZUO Liu-yi LEI Zi-qiang et al. |
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| Affiliation: | WANG Lan,ZUO Liu-yi,LEI Zi-qiang,et al.Department of Pharmacy,First Affitiated Hospital,Chongqing University of Medical Sciences,Chonging 400016,China |
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| Abstract: | Objective To prepare the mixture bismuth composition(MBC) and to establish the quality control for this preparation.Methods Bismuth ammonium citrate was taken as the chief component with potassium chloride,glycerol, tincture aurante,etc for the preparation of MBC.The bismuth content of the preparation was determined by complex titration,and stability of the preparation was examimed,too.Results The procedure of preparation was simple,and the quantitative determination was quick,and accurate while the quality was reliable.Conclusion The procedure described here can be used to prepare the mixture bismuth composition. |
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| Keywords: | Mixture bismuth composition Bismuth ammonium citrate Preparation Quality control |
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