老年原发性高血压患者合并血脂异常与血糖水平的关系

目的：探讨老年原发性高血压（essential hypertention，EH）患者血糖水平与血脂、胰岛素水平的关系。方法：比较EH组与对照组及EH按血糖水平分组后与对照组的总胆固醇（total cholesterol，TC）、三酰甘油（triglyceride,TG）、高密度脂蛋白胆固醇（high density lipoprotein cholesterol，HDL-C）、低密度脂蛋白胆固醇low density lipoprotein cholesterol，LDL-C）和空腹血浆胰岛素（fasting plasma insulin，FINS）的水平。结果：EH组患者血脂成分及胰岛素水平均较对照组有显著性差异（P〈0．01，P〈0．05）。EH组与对照组相比，EH组的TC、TG、LDL-C、FINS显著升高（P〈0．01，P〈0．05），HDL-C显著降低（P〈0．05）。结论：EH患者胰岛素抵抗（insulin-resistance，IR）水平增加是血脂异常的原因之一，血脂异常的程度随糖尿病病程的进展而加重。

Relationship between lipid phenotype and levels of plasma glucose in elderly patients with hypertension

Objective: Evaluating the effects of plasma glucose level in lipid phenotype and levels of plasma insulin in elderly hypertension.Methods: Comparing the TC,TG,HDL-C,LDL-C,FINS and glucose between the hypertensive group and control group,the subgroup and the control group.Results: Compared with the control group, the lipid phenotype and insulin levels were abnormal greatly in hypertensives(P<0.01,P<0.05),in subgroups,the level of TC,TG,LDL-C and FINS increased and the HDL-C level decreased than those of control group(P<0.01,P<0.05). Conclusion: The increasing of insulin-resistance may be one of the causes of dyslipidemia in EH patients and the dyslipidemia phenotype related with the increased type 2 diabetes mellitus.