注射用穿琥宁与5种输液配伍的稳定性观察

目的观察注射用穿琥宁与临床常用的5种药物配伍后的稳定性。方法使用各精密仪器测量观察注射用穿琥宁与5种药物在常温下配伍后0、1、2、4、8 h内外观、含量、微粒、pH值和紫外光吸收度的变化。结果注射用穿琥宁粉针剂与头孢唑林钠、地塞米松磷酸钠注射液、甲硝唑、5%葡萄糖注射液、0.9%氯化钠注射液配伍,配伍液的外观、含量、微粒、pH值和紫外光吸收度均无明显变化。结论注射用穿琥宁在临床上可与此5种药物配伍应用。

Observation on stability of the kalii dehydrographolidi succinatis injection with five infusions

Objective To observe the stability of the kalii dehydrographolidi succinatis injection with five infusions in clinical.Methods The precision instruments w ere used to measure the injection dehydrographolidi w ith five drugs in the compatibility of 0,1,2,4,8 h at room temperature in appearance,content,particles,pH and UV absorbance changes.Results There w as no change of compatibility fluid appearance,content,particles,pH and UV absorbance after compatibility of the kalii dehydrographolidi succinatis w ith cefazolin sodium,dexamethasone sodium phosphate injection,metronidazole,5% glucose injection and 0.9% sodium chloride injection.Conclusion The kalii dehydrographolidi succinatis could be compatible application with the 5 drugs in clinical.