老年人主动脉弓及颈内动脉粥样硬化斑块与脑血管病的相关性研究

目的探讨老年人升主动脉、主动脉弓及颈内动脉粥样硬化斑块与脑血管病的关系。方法选择25倒死于脑血管病的患者作为脑卒中组,15例死于非心脑血管病的患者为对照组,两组取升主动脉、主动脉弓和颈内动脉处相关组织,镜下观察动脉粥样硬化斑块的病理性质。结果脑卒中组患者升主动脉斑块有12例,颈内动脉斑块有12例,以扁平斑、硬斑和软斑为主;主动脉弓和颈内动脉入口处斑块有18例,其中溃疡斑和出血性斑块多见;对照组患者上述位置斑块各有5例.以散在硬斑为主,有少量软斑。结论老年人主动脉弓及颈内动脉入口处的溃疡斑、出血性斑块破裂可导致血栓形成,是引发脑血管病的危险因素。

Study on relationship of atherosclerotic plaques of aorta and internal carotid artery to cerebrovascular diseases in old patients

Objective To discuss the relationship of the plaques in aorta ascendens,arcus aortae and internal carotid artery to cerebrovascular disease(CVD).Methods Corpses of 25 patients died of CVD were selected as group Ⅰ, and corpses of 15 patients died of other diseases served as group Ⅱ. The ascending aorta,aortic arch and internal carotid artery were taken from both groups,and the morphology, number, distribution and pathological structure of the plaques were observed under the microscope. Results In group Ⅰ, atherosclerotic plaques were detected in ascending aortas of 12 cases and internal carotid arteries of 12 cases,and were mainly flat,hard and soft plaques. Atheroslerotic plaques in aortic arches and entrances to internal carotid arteries were detected in 18 cases, and majority were ulcerative and hemorrhagic plaques. In group Ⅱ, scattered plaques were seen in these three places of 5 cases,and were mainly hard plaques with a few soft plaques. Conclusion Rupture of ulcerative plaques and hemorrhagic plaques in aortic arches and. entrances to internal carotid arteries can lead to thrombosis which is the risk factor for CVD.