| 血清脂联素和抵抗素与2型糖尿病及其大血管病变相关 |
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| 引用本文： | 赵志刚,张会峰,张春玲,汪艳芳,马书平,袁慧娟,苏永,王遂军.血清脂联素和抵抗素与2型糖尿病及其大血管病变相关[J].中华内分泌代谢杂志,2008,24(2). |
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| 作者姓名： | 赵志刚 张会峰 张春玲 汪艳芳 马书平 袁慧娟 苏永 王遂军 |
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| 作者单位： | 1. 河南省人民医院二内分泌科,郑州,450003
2. 河南省财经学院外语系 |
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| 摘 要： | 测定2型糖尿病患者血清脂联素和抵抗素水平,发现2型糖尿病组血清脂联素浓度(2.51±1.42)mg/L低于正常对照组(5.26±0.78)mg/L,2型糖尿病大血管病变组为(1.38±0.77)mg/L又低于非大血管病变组(3.66±0.91)mg/L,差异均有统计学意义(均P＜0.01).2型糖尿病组血清抵抗素浓度(7.07±1.11)μg/L高于正常对照组(6.09±0.47)μg/L,2型糖尿病大血管病变组为(7.96±0.65)μg/L又高于非大血管病变组(6.10±0.43)μg/L,差异均有统计学意义(均P＜0.01).
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| 关 键 词： | 脂联素 抵抗素 糖尿病 2型 大血管并发症 |
Association of serum adiponectin and resistin with type 2 diabetes mellitus and its macrovascular complications |
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| ZHAO Zhi-gang,ZHANG Hui-feng,ZHANG Chun-ling,WANG Yan-fang,MA Shu-ping,YUAN Hui-juan,SU Yong,WANG Sui-jun.Association of serum adiponectin and resistin with type 2 diabetes mellitus and its macrovascular complications[J].Chinese Journal of Endocrinology and Metabolism,2008,24(2). |
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| Authors: | ZHAO Zhi-gang ZHANG Hui-feng ZHANG Chun-ling WANG Yan-fang MA Shu-ping YUAN Hui-juan SU Yong WANG Sui-jun |
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| Abstract: | The concentration of serum adiponectin (2.51±1.42)mg/L] was lower in the group of patients with type 2 diabetes mellitus as compared with that in normal control group (5.26±0.78)mg/L , P＜0.01]. The concentration of serum adiponectin was lower in the diabetics with macrovascular complications (MVC) (1.38±0.77)mg/L] as compared with those without macrovascular complication (3.66±0.91)mg/L]. The concentration of serum resistin was higher in the diabetic group as compared with that in control group(7.07±1.11 vs 6.09±0.47)μg/L, P＜0.01]. It was also higher in patients with MVC (7.96±0.65)μg/L] compared with those without MVC (6.10±0.43)μgL, P＜0.01]. |
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| Keywords: | Adiponectin Resistin Diabetes mellitus type 2 Macrovascular complications |
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