超声造影引导经皮穿刺活检诊断胰腺占位性病变

目的探讨应用CEUS引导经皮穿刺活检对胰腺占位性病变的临床应用价值。方法对因胰腺占位性病变需行穿刺活检、但常规超声定位困难的49例患者行CEUS引导下经皮穿刺活检,以所取组织能够作出明确病理诊断为取材满意;随访至少6个月,以术后病理诊断或随访影像学检查结果为最终临床诊断。结果本组穿刺活检满意率为95.92%(47/49),取材满意者穿刺活检的诊断准确率为97.87%(46/47)。术后恶心呕吐、发热及胆汁性腹膜炎各1例(1/49,2.04%)。结论对于常规超声不能准确定位的胰腺占位性病变,以CEUS引导穿刺可以提高取材的准确性,降低并发症发生率。

Contrast enhanced ultrasound guided percutaneous biopsy in diagnosis of pancreatic space occupying lesions

Objective To explore the clinical value of CEUS guided percutaneous biopsy in patients with pancreatic space occupying lesions. Methods Totally 49 patients with pancreatic masses underwent percutaneous biopsy guided by CEUS. All of the biopsy targets could not be confidently localized with conventional ultrasound. When the acquired tissues could give definite diagnosis, the sample was defined as satisfactory. Follow-up lasted at least 6 months. The results of the pathological diagnosis or follow-up imaging studies were taken as the final diagnosis. Results The satisfactory rate of percutaneous biopsy was 95.92% (47/49). The accuracy of biopsy with satisfactory sampling was 97.87% (46/47). The complications included nausea and vomiting, fever and biliary peritonitis (each n=1, 1/49, 2.04%). Conclusion For pancreatic space occupying lesions which biopsy targets could not be definitely localized with conventional ultrasound, CEUS-guided percutaneous biopsy can improve the accuracy of puncture and reduce the incidence of complication.