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| 枸骨叶中的三萜类成分 | |
| 引用本文： | 姚志容,李军,周思祥,张芸,屠鹏飞.枸骨叶中的三萜类成分[J].中国中药杂志,2009,34(8):999. |
| 作者姓名： | 姚志容 李军 周思祥 张芸 屠鹏飞 |
| 作者单位： | 北京大学,药学院,天然药物及仿生药物国家重点实验室,北京,100191 |
| 基金项目： | 国家自然科学基金项目(30672608)；教育部长江学者与创新团队基金项目(985-2-063-112) |
| 摘 要： | 目的:研究枸骨叶中的化学成分.方法:运用硅胶、Sephaclex LH-20柱色谱及硅胶薄层色谱等方法对枸骨叶中的化学成分进行分离,通过理化常数、质谱和核磁技术鉴定化合物.结果:从枸骨叶中分离并鉴定了6个化合物,分别为20α-羟基-乌索酸(1),阿江榄仁酸(2),23-羟基-乌索酸(3),27-O-(Z)-香豆酰基-乌索酸(4),27-O-(E)-香豆酰基-乌索酸(5),积雪草酸(6).结论:化合物1,2为首次从该属植物中分得到,化合物3～6为首次从该植物中分离得到. |
| 关 键 词： | 冬青属 枸骨 化学成分 三萜 |
Triterpenoids from leaves of Ilex cornuta |
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| TAO Zhi-Rong,Li-Jun,Zhou-Sai-Xiang,Zhang-Yun,Tu-Feng-Fei-.Triterpenoids from leaves of Ilex cornuta[J].China Journal of Chinese Materia Medica,2009,34(8):999. | |
| Authors: | TAO Zhi-Rong Li-Jun Zhou-Sai-Xiang Zhang-Yun Tu-Feng-Fei- |
| Affiliation: | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
| Abstract: | Objective: To investigate the chemical constituents of Ilex cornuta. Method: The chemical constituents were isolated by column chromatographic methods. And the structures were identified by spectral data. Result: Seven compounds were isolated and identified as follows: 2α-hydroxy ursolic acid (1), arjunolic acid (2), 23-hydroxy ursolic acid (3), 27-O-p-(Z)-coumaroyl ursolic acid (4), 27-O-p-(E)-coumaroyl ursolic acid (5), asiatic acid (6). Conclusion: Compound 1, 2 were obtained from this genus for the first time and 3-6 from this plant for the first time. |
| Keywords: | Ilex Ilex cornuta chemical constituents triterpenoids |
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