| S-甲基-L-半胱氨酸的合成 |
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| 引用本文： | 马程军,姚斐,张关永.S-甲基-L-半胱氨酸的合成[J].化学世界,2003,44(7):370-372. |
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| 作者姓名： | 马程军 姚斐 张关永 |
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| 作者单位： | 华东理工大学化学与制药学院,上海,200237 |
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| 摘 要： | 以 L-半胱氨酸为原料 ,磷酸三甲酯为甲基化试剂合成了 S-甲基 - L-半胱氨酸。研究了 p H值、温度等反应条件对产品品质和收率的影响。发现在严格控制 p H为 7.0 ,反应温度不高于 37°C的条件下 ,并不出现消旋作用。这一合成路线可用于工业上大规模生产
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| 关 键 词： | L-半胱氨酸 磷酸三甲酯 S-甲基-L-半胱氨酸 |
| 文章编号： | 0367-6358(2003)07-0370-03 |
Synthesis of S-Methyl-L-cysteine |
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| MA Cheng jun,YAO Fei,ZHANG Guan yong.Synthesis of S-Methyl-L-cysteine[J].Chemical World,2003,44(7):370-372. |
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| Authors: | MA Cheng jun YAO Fei ZHANG Guan yong |
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| Abstract: | S Methyl L cysteine was synthesized with L cysteine as the starting material and trimethyl phosphate as the methylating agent. The influence of temperature and pH value on the yield and quality of product was studied. The result showed that racemization was not observed when the pH value was 7 and the reaction temperature was lower than 37°C. This method is suitable for large scale production. |
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| Keywords: | L cysteine trimethyl phosphate S methyl L cysteine |
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