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| 肝癌合并梗阻性黄疸的双介入治疗临床研究 | |
| 引用本文： | 王成刚,沈杰,龚高全,邱伟利,陈越,王良文.肝癌合并梗阻性黄疸的双介入治疗临床研究[J].中国现代医生,2008,46(19):7-9. |
| 作者姓名： | 王成刚 沈杰 龚高全 邱伟利 陈越 王良文 |
| 作者单位： | 1. 复旦大学附属中山医院分部放射科,上海,200052 2. 解放军第四五五医院肿瘤科,上海,200052 3. 复旦大学附属中山医院放射科,上海,200032 4. 上海市岳阳中西医结合医院肿瘤科,上海,200437 |
| 摘 要： | 目的探讨胆道支架置放结合动脉化疗栓塞治疗肝癌合并梗阻性黄疸的疗效。方法24例肝癌合并梗阻性黄疸患者行经皮穿肝胆道引流术后，采用置放胆道支架（总计31枚）结合动脉化疗栓塞（总计51次）的治疗方法。分别观察血清胆红素下降程度，手术并发症，并随访患者生存期和胆道支架维持通畅时间。结果24例患者PTCD成功率100％，治疗后总胆红素明显下降，由（201．8±154．7）μmol／L降至（120．8±106．7）μmol／L。引流通畅中位时间6．1个月，全组生存中位时间6．2个月。结论胆道支架置放结合动脉化疗栓塞治疗肝癌合并梗阻性黄疸有较好疗效。 |
| 关 键 词： | 肝癌 梗阻性黄疸 介入治疗 |
The Clinical Analysis of a Double Interventional Therapy in 24 Hepatocellular Carcinoma Patients with Obstructive Jaundice |
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| Authors: | WANG Chenggang SHEN Jie GONG Gaoquan QIU Weili CHEN Yue WANG Liangwen |
| Affiliation: | WANG Chenggang SHEN Jie GONG Gaoquan QIU Weili CHEN Yue WANG IAangwen(1.Department of Radiology,Branch of Zhongshan Hospital,Fudan University,Shanghai 200052;2.Department of Medical Oneology,The PLA No.455 Hospital, Shanghai 200052; 3.Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032; 4.Department of Medical Oncology, Shanghai Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai 200437) |
| Abstract: | Objective To investigate the therapeutic effect of biliary stents combining transcatheter arterial chemoembolization（TACE）to treat hepatocellular carcinoma（HCC ）with obstructive jaundice. Methods After percutaneous transhepatic choleductus drainage（PTCD）in 24 HCC patients with obstructive jaundice, they were treated with the methods of biliary stents （total： 31 ） and TACE（total：51 ）. The descending level of bilirubin and complications of operation were observed. To follow up the survival time and the time of biliary stent sustaining unobstructed. Results The PTCD successful rate was 100% in X HCC patients. The complications happened in X HCC patients. The total bifirubin level decreased ,significantly from（201.8 ± 154.7 ） μL mol/L to（ 120.8 ± 106.7 ） μL mol/L. The median time of unobstructed draining was 6.1 months. The median survival time was 8.1 months. Conclusion The better therapeutic effect was obtained in HCC with obstructive jaundice patients treated with biliary stent combining transcatheter arterial chemoembolizadon（TACE）. |
| Keywords: | Hepatocellular carcinoma Obstructive jaundice Interventional therapy |
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