磁共振扩散成像在肝占位性病变中的应用

目的评价磁共振扩散加权成像在肝占位性病变诊断和鉴别诊断中的作用。方法对60例肝脏占位性病变的病人行磁共振扩散加权成像（DWI）,并测量表面扩散系数ADC值,进行对比分析。结果肝细胞癌、肝转移瘤、肝血管瘤、肝囊肿ADC值分别为（1.34±0.12）×10^-3mm^2/s、（1.79±0.21）×10^-3mm^2/s、（3.23±0.28）×10^-3mm^2/s、（4.07±0.65）×10^-3mm^2/s,肝脏良性肿瘤的ADC值明显高于恶性肿瘤的ADC值,且两者间差异有统计学意义（P〈0.05）,而肝转移瘤和原发肝癌的ADC值之间差异无统计学意义,鉴别诊断较困难。结论磁共振扩散加权成像为肝占位性病变的诊断及鉴别诊断提供一种新的方法,特别对良、恶性病变的鉴别有重要价值。

Application of magnetic resonance diffusion weighted imaging for detecting hepatic lesions

Objective To evaluate the efficacy of MR diffusion-weighted imaging （DWI） values in diagnosis and identify of liver lesions. Methods A total of 60 patients with hepatic lesions MRI findings were retrospectively enrolled. DW-MRI was performed with b-factors of 0 and 500 s/mm2. Mean ADC measurements were calculated.Results On DWI（（b=500 s/mm^2）,The mean ADC value of normal liver was （1.51 ±0.16）×10^-3mm2/s. The mean ADC values of hepatocellular carcinoma,metastasis ,hemangioma and cyst were （1.34±0.12）×10^-3mm^2/s,（1.79±0.21）×10^-3mm^2/s,（3.23±0.28）×10^-3mm^2/s,and （4.07±0.65）×10^-3mm^2/s,respectively. A significant difference was showed between hepatic malignances and hepatic cyst and hemangioma （P0.05）.Conclusion MR DWI and ADC values are useful in diagnosis of benign from malignant hepatic lesions.