| 褶合曲线分析法同时测定小儿复方苯巴比妥片中四组分的含量 |
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| 引用本文： | 高金波,丁立新,侯巍,张羽男,吕宁.褶合曲线分析法同时测定小儿复方苯巴比妥片中四组分的含量[J].药学实践杂志,2003,21(4):214-216. |
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| 作者姓名： | 高金波 丁立新 侯巍 张羽男 吕宁 |
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| 作者单位： | 1. 佳木斯大学化学与药学院,黑龙江,佳木斯,154007
2. 齐齐哈尔铁路中心医院,黑龙江,齐齐哈尔,161000 |
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| 摘 要： | 目的：不经分离同时测定小儿复方苯巴比妥片中四组分的含量。方法：以褶合光谱为基础，结合当前最优秀的数值计算法——偏最小二乘法(PLS法)利用计算机信息处理技术的褶合曲线分析法。结果：小儿复方苯巴比妥片中阿司匹林、非那西丁、咖啡因和苯巴比妥四组分的平均回收率及相对标准偏差(RSD)分别为99．75，0．92％；100．47，0．56％；99．82，1．12％；100．08，0．86％。结论：该方法可以用于小儿复方苯巴比妥片剂的质量监控。
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| 关 键 词： | 小儿复方苯巴比妥片 组分 含量测定 褶合曲线分析法 数值计算法 |
| 文章编号： | 1006-0111(2003)04-0214-03 |
| 收稿时间： | 2003/3/11 0:00:00 |
| 修稿时间： | 2003年3月11日 |
Application of convolution curve method for simultaneous determination of four components in the compound children's phenobarbital tablet |
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| GAO Jin-bo,DING Li-xin,HOU Wei,ZHANG Yu-nan and LU Ning.Application of convolution curve method for simultaneous determination of four components in the compound children''s phenobarbital tablet[J].The Journal of Pharmaceutical Practice,2003,21(4):214-216. |
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| Authors: | GAO Jin-bo DING Li-xin HOU Wei ZHANG Yu-nan and LU Ning |
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| Affiliation: | College of Chemistry and Pharmay, Jiamusi University, Jiamusi 154007, China;College of Chemistry and Pharmay, Jiamusi University, Jiamusi 154007, China;College of Chemistry and Pharmay, Jiamusi University, Jiamusi 154007, China;College of Chemistry and Pharmay, Jiamusi University, Jiamusi 154007, China;Qiqihar Railway Hospital, Qiqihaer 161000, China |
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| Abstract: | OBJECTIVE: Without any separation, simultaneous determination of four main components in the compound children's phenobarbital tablet. METHODS: Based on convolution spectrometry with the excellent cacu-lation method-PLS method used convolution spectrometry of computer information process technology. RESULTS: Components of compound children's phenobarbital tablet are aspirin, phenacetin, caffine and phenobarbital . Their average recoveries and RSD were 99. 75 ,0. 92% : 100. 47 ,0. 56% : 99. 82,1. 12% : 100. 08 ,0. 86% . CONCLUSION: The method is used for qualitative control of compound children's phenobarbital tablet. |
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| Keywords: | convolution curve analytical system children's phenobarbital tablet aspirin phenacetin caffine phenobarbital |
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