Inactivation of the infectivity of two highly pathogenic avian influenza viruses and a virulent Newcastle disease virus by ultraviolet radiation |
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| Authors: | David Sutton Elizabeth W Aldous Caroline J Warren Chad M Fuller Dennis J Alexander Ian H Brown |
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| Affiliation: | Virology Department, Animal Health and Veterinary Laboratories Agency, New Haw, Surrey, UK |
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| Abstract: | Exposure of a virulent isolate of Newcastle disease virus (NDV) and two highly pathogenic avian influenza (HPAI) viruses, one of H7N1 subtype and the other H5N1 subtype, to a continuous ultraviolet B flux of approximately 90µW/cm2, which models solar ultraviolet radiation, resulted in an exponential decline in infectivity with time. The time taken for a reduction in titre of 1 log10 median tissue culture infectious dose for each virus was: NDV, 69 min; H7N1 HPAI virus, 158 min; and H5N1 HPAI, virus 167 min. |
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