| 子宫内膜异位症患者治疗前后血清hs—CRP、IL--6、IL--8和M—CSF测定的临床意义 |
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| 引用本文： | 陈晓超,刘洪书,周东霞,张力敏.子宫内膜异位症患者治疗前后血清hs—CRP、IL--6、IL--8和M—CSF测定的临床意义[J].放射免疫学杂志,2008,21(4):304-305. |
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| 作者姓名： | 陈晓超 刘洪书 周东霞 张力敏 |
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| 作者单位： | 1. 江苏省沭阳县人民医院妇产科,223600
2. 连云港市人民医院,222002 |
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| 摘 要： | 目的：探讨了子宫内膜异位症患者治疗前后血清hs-CRP、IL-6、IL-8和M-CSF水平的变化及临床意义。方法：采用放射免疫分析和免疫比浊法对33例子宫内膜异位症患者进行了血清hs-CRP、IL-6、IL-8和M-CSF测定，并与35名正常健康人作比较。结果：在治疗前血清hs-CRP、IL-6、IL-8和M-CSF水平非常显著地高于正常人组（P〈0．01），经系统治疗后3个月，则与正常人比较无显著性差异（P〉0．05）。结论：检测子宫内膜异位症患者血清hs-CRP、IL-6、IL-8和M-CSF水平的变化对探讨其发病机理、预防和指导用药均具有重要的临床价值。
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| 关 键 词： | 子宫内膜异位症 超敏C-反应蛋白 白细胞介素-6 白细胞介素-8 巨噬细胞集落刺激因子 |
Clinical Significance of Measurement of Changes of Serum hs- CRP, IL-6, IL-8 and M-CSF Levels After Treatment in Patients with Endometriosis |
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| Chen Xiaochao,Liu Hongshu,Zhou Dongxia,et al..Clinical Significance of Measurement of Changes of Serum hs- CRP, IL-6, IL-8 and M-CSF Levels After Treatment in Patients with Endometriosis[J].Journal of Radioimmanology,2008,21(4):304-305. |
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| Authors: | Chen Xiaochao Liu Hongshu Zhou Dongxia |
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| Abstract: | Objective To explore the significance of changes of serum hs-CRP,IL-6,IL-8 and M-CSF levels after treatment in patients with endometriosis.Methods Serum IL-6,IL-8,M-CSF(with RIA),hs-CRP(with immuneturbidity method)levels were determined in 33 patients with endometrosis both before and after treatment as well as in 35 controls.Results Before treatment,the serum hs-CRP,IL-6,IL-8 and M-CSF levels were significantly higher in the patients than those in controls(P<0.01).After treatment for three months,the levels in patients were not much different from those in controls(P>0.05).Conclusion Detection of serum hs-CRP,IL-6,IL-8 and M-CSF levels might reflect the progress of diseases in patients with endometriosis. |
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| Keywords: | endometriosis high sensitive-creactive protein(hs-CRP) interleukin-6(IL-6) interleukin-8(IL-8) macrophage colony-stimulating factor(M-CSF) |
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