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奥沙利铂原料药3种含量测定方法比较
引用本文:费瑞娟,陈祥峰,任凤.奥沙利铂原料药3种含量测定方法比较[J].中国当代医药,2010,17(34):57-58.
作者姓名:费瑞娟  陈祥峰  任凤
作者单位:[1]江苏省电业职工疗养院,江苏无锡214164 [2]江苏奥赛康药业有限公司,江苏南京211112
摘    要:目的:建立奥沙利铂原料药的含量测定方法。方法:采用反相高效液相色谱法测定奥沙利铂原料药的含量,并与UV法及炽灼残渣法进行比较。结果:3种检测方法均具可行性。结论:高效液相色谱法测定干扰小,操作方便,结果准确。

关 键 词:奥沙利铂  HPLC  含量测定

Determination of Oxaliplatin by three methods
Authors:FEI Ruijuan  CHEN Xiangfeng  REN Feng
Affiliation:1.Jiangsu employee arcadia resorts of electricity power,Jiangsu Province,Wuxi 214164,China;2.Jiangsu Aosaikang Pharmaceutical Co.,Ltd,Jiangsu Province,Nanjing 211112,China)
Abstract:Objective:To develop a method for determining the content of oxaliplatin.Methods:RP-HPLC,UV and residue on ignition method were used to determine oxaliplaitin,respectively,and the results were compared with each other.Results:All the three mothods were feasible for determining oxaliplatin.Conclusion:RP-HPLC method is simple and more accurate.
Keywords:Oxaliplatin  HPLC  Content
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