| 癫痫宁胶囊的药效学研究 |
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| 引用本文： | 于肯明,白建平,李月英,王树华,李志华,樊碧发,许维祯.癫痫宁胶囊的药效学研究[J].大同医学专科学校学报,1997(1). |
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| 作者姓名： | 于肯明 白建平 李月英 王树华 李志华 樊碧发 许维祯 |
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| 作者单位： | 大同医专教务处，大同医专药理教研室，大同医专药理教研室，大同医专药理教研室，大同医专药理教研室，大同医专药理教研室，大同医专药理教研室 副处长 037008 |
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| 摘 要： | 采用最大电休克发作(MES)法,戊四氮最小阈发作(MET)法,协同巴比妥作用法以及小鼠耐缺氧法,观察癫痫宁对动物惊厥,催眠及耐缺氧的影响,同时还观察对小鼠的毒性作用。实验表明、癫痫宁4.5g*kg~(-1)能对抗小鼠的MES和MET,能增强巴比妥类药物的催眠作用以及延长小鼠常压耐缺氧存活时间,且毒性甚小。
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| 关 键 词： | 癫痫宁 戊四氮 催眠 缺氧 |
Studys on pharmacodynamics of Dia Xian Nin capsule |
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| Yu Kenming,Bai Jianping,LiYaying et al.Studys on pharmacodynamics of Dia Xian Nin capsule[J].Journal of Datong Medical College,1997(1). |
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| Authors: | Yu Kenming Bai Jianping LiYaying |
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| Affiliation: | Dapt of phar Datong Medical college |
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| Abstract: | The pharmacoclynamics of the Dian Xian Nin were studied in Maximal elec-troshock seizure (MES).Mehrazol minirml threshold seizure(MET)hypnotic effect and oxygen consumption The results showed that Dianxian Nin had prective effects aganist MES, MET in miee,It could synative the hypnotic effect of phenobabital sodium and reduce o2 consumption In addition,it bad no significant toxicity. |
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| Keywords: | Dian Xian Nin hypnotic effect Oxyyen consumption |
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