| 环丙沙星在溶液中固液表面能的测定 |
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| 引用本文： | 刘勇,王静康,尹秋响.环丙沙星在溶液中固液表面能的测定[J].化学工业与工程,2002,19(5):354-359,373. |
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| 作者姓名： | 刘勇 王静康 尹秋响 |
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| 作者单位： | 天津大学化工学院,天津,300072 |
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| 摘 要： | 采用激光法测定了环丙沙星在纯水和水－乙醇溶液（水体积分数23％）中的溶解度，介稳区和不同条件下的诱导期。根据经典成核理论和诱导期理论，推导了固液表面能与诱导期的理论关系，应用该理论关系计算了环丙沙星在溶液中的固液表面能，为环丙沙星初级成核与晶体生长研究提供了重要的参数。
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| 关 键 词： | 溶液 固液表面能 测定 环丙沙星 溶解度 介稳区 诱导期 表面能 |
| 文章编号： | 1004-9533(2002)05-0354-06 |
Determination the Interfacial Energy of Solid-Ligaid in Ciprofloxacin Hydrochloride Monohydrate Solution |
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| LIU Yong,WANG Jing-kang,YIN Qiu-xiang.Determination the Interfacial Energy of Solid-Ligaid in Ciprofloxacin Hydrochloride Monohydrate Solution[J].Chemical Industry and Engineering,2002,19(5):354-359,373. |
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| Authors: | LIU Yong WANG Jing-kang YIN Qiu-xiang |
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| Abstract: | The solubility,metastable zone and induction period of ciprofloaxicn hydrochloride monohydrate in water or 23% (vol) water\|ethanol solution are measured by laser method.Based on the classic nucleation theory and the induction period theory,a general expression of the relationship between the interface energy and the relative supersolubility is established.Using this expression,the interface energy of ciprofloaxicn hydrochloride monohydrate in solution at various conditions are evaluated in order to supply important parameters for studying on the primary nucleation and crystal growth. |
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| Keywords: | ciprofloaxicn hydrochloride monohydrate solubility metastable zone induction period interfacial energy |
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