磁共振扩散峰度成像的临床研究进展

磁共振扩散峰度成像(diffusional kurtosis imaging,DKI)是一种可量化组织内水分子扩散非高斯运动的磁共振新技术,是扩散张量成像技术的延伸,对于描绘组织微观结构具有独特优势。DKI技术在神经系统已有较多研究,并已取得较好的成果。近年来,DKI逐渐应用于其他系统疾病研究,也取得了初步成果,展现出一定的临床价值。现综述DKI的成像原理及其在全身各系统中的研究进展。

Research advances in diffusional kurtosis imaging

Diffusion kurtosis imaging (DKI) is an emerging diffusion index to quantify non-Gaussian diffusional process in vivo and an extension of the technology of diffusion tensor imaging, particularly having unique advantages for characterizing microstructure of tissues. The technology of DKI has been studied in the nervous system and has made good progresses. In recent years, DKI is gradually applied to the researches of other different systems and has also obtained preliminary results, which displayed certain clinical values. This article proposed to summary the technic principles and application advances in various systems for DKI.