早期肠道营养预防烧伤后应激性溃疡

目的 探讨早期肠道营养预防严重烧伤患者并发应激性溃疡上消化道出血的疗效.方法 78例严重烧伤患者(烧伤面积大于50%)被随机分成抑酸治疗组(38例)与早期肠道营养组(40例).抑酸治疗组在烧伤后48小时内仅用制酸药:法莫替丁20毫克,每12小时1次.早期肠道营养组在烧伤后48小时内鼻饲能全力进行早期肠道营养,不用制酸药和静脉营养.观察并比较两组烧伤后应激性溃疡出血的发生率.结果 抑酸治疗组应激性溃疡出血发生率21.05%(8/38),早期肠道营养组应激性溃疡出血发生率7.5%(3/40),经统计学比较,有显著性差异(P＜0.01).结论 早期肠道营养对严重烧伤患者并发应激性溃疡上消化道出血的预防疗效优于抑酸治疗;早期肠道营养对严重烧伤患者的胃肠道粘膜有一定的保护作用,一定程度上预防了烧伤后应激性溃疡出血的发生.

The effects of early enteral nutrition on the prophylaxis of stress ulcer in the severely burned patient

Objective To observe the clinic effects of early enteral nutrition on the prophylaxis of stress ulcer in the severely burned patient.Methods 78 severely burned patients were randomly divided into two groups:early enteral nutrition group(40 patients)and anti-acid therapy group(38 patients).The incidence of gastrointestinal hemorrhage was detected.Results The incidence rates of gastrointestinal hemorrhage were 3/40 and 8/38 in early enteral nutrition group(40 patients)and anti-acid therapy group respectively.Conclusions Early enteral nutrition may prevent stress ulcer in the severely burned patient.