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Interleukin-11 Overexpression and M2 Macrophage Density are Associated with Angiogenic Activity in Proliferative Diabetic Retinopathy
Authors:Ahmed M Abu El-Asrar  Ajmal Ahmad  Eef Allegaert  Mohammad Mairaj Siddiquei  Priscilla W Gikandi  Gert De Hertogh
Affiliation:1. Department of Ophthalmology, College of Medicine, King Saud University , Riyadh, Saudi Arabia;2. Dr. Nasser Al-Rashid Research Chair in Ophthalmology, College of Medicine, King Saud University , Riyadh, Saudi Arabia abuasrar@KSU.edu.sa;4. Department of Ophthalmology, College of Medicine, King Saud University , Riyadh, Saudi Arabia;5. Laboratory of Histochemistry and Cytochemistry, University of Leuven , Leuven, Belgium
Abstract:ABSTRACT

Purpose

To investigate the expression of IL-11 and its receptor IL-11Rα and to quantify density of CD163+ M2 macrophages in proliferative diabetic retinopathy (PDR).
Keywords:Angiogenesis  CD163  IL-11  IL-11Rα  inflammation  M2 macrophages  proliferative diabetic retinopathy
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