胼胝体梗死临床特点分析

目的探讨胼胝体梗死患者的临床表现、影像学表现以及预后。方法纳入胼胝体梗死患者11例,对其临床特征及头颅CT、MRI表现及预后等进行回顾性分析,总结胼胝体梗死的临床特点。结果胼胝体梗死患者中,梗死范围局限于胼胝体的局限病灶患者占27.3%,合并胼胝体外梗死的弥散性病灶患者占72.7%。胼胝体梗死患者临床可表现为失语、肌力减退、智能障碍、小便失禁、感觉障碍、意识障碍、共济失调、情感障碍等症状,病变除累及胼胝体外还多合并基底节区、额叶、顶叶、颞叶等部位梗死。随访1年,患者痊愈或症状改善为10例(90.9%),恶化1例(9.1%)。结论胼胝体梗死患者临床表现复杂多变,头颅MRI对胼胝体梗死的诊断具有重要价值,经积极治疗预后良好。

Clinical characteristics of corpus callosum infarction

Objective To discuss the clinical symptoms, imaging manifestations and prognosis in the patients with corpus callosum infarction. Methods The patients （n=11） were chosen and their clinical symptoms, manifestations of head CT and MRI and prognosis were retrospectively analyzed, and the clinical characteristics of corpus callosum infarction were summed up. Results The percentage of patients with local focus limited in corpus callosum counted for 27.3%, and that of those with diffuse focus, 72.7%. The clinical symptoms included aphasia, loss of muscle tone, mental retardation, aconuresis, sensory disturbance, disturbance of consciousness, ataxia and affective disorder. Besides of corpus callosum, basal ganglia, frontal lobe, parietal lobe and temporal lobe were commonly involved. After followed up for one year, there were 10 patients （90.9%） cured or relieved, and one case （9.1%） deteriorated. Conclusion The clinical symptoms are complicated in patients with corpus callosum infarction, and head MRI is important to the diagnosis of corpus callosum infarction. The prognosis will be good after active treatment.