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根皮素乙酰阿魏酸酯的合成及抗氧化活性研究
引用本文:李翠苹,余燕影,曹树稳.根皮素乙酰阿魏酸酯的合成及抗氧化活性研究[J].天然产物研究与开发,2012,24(3):316-320.
作者姓名:李翠苹  余燕影  曹树稳
作者单位:1. 南昌大学化学系,南昌,330031
2. 南昌大学化学系,南昌330031;南昌大学食品科学与技术国家重点实验室,南昌330047
摘    要:以阿魏酸和根皮素为原料,合成了三种根皮素乙酰阿魏酸酯,采用IR、1H NMR、13C NMR和HPLC-MS对其结构进行表征.并测定根皮素及其酯的还原能力、清除DPPH自由基及·OH自由基能力,结果表明根皮素乙酰阿魏酸酯的抗氧化活性显著优于根皮素.

关 键 词:根皮素  阿魏酸  酯化  合成  抗氧化

Synthesis and Antioxidant Activity of Phloretin Acetylferulic Acid Esters
LI Cui-ping , YU Yan-ying , CAO Shu-wen.Synthesis and Antioxidant Activity of Phloretin Acetylferulic Acid Esters[J].Natural Product Research and Development,2012,24(3):316-320.
Authors:LI Cui-ping  YU Yan-ying  CAO Shu-wen
Affiliation:1,2* 1Department of Chemistry,Nanchang University,Nanchang 330031,China; 2State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China;
Abstract:Three new compounds were firstly synthesized by ferulic acid and phloretin.The target compound was characterized by IR,1H NMR,13C NMR and HPLC-MS,respectively.Reducing power,DPPH and ·OH radical scavenging assays were carried out to evaluate the antioxidant and free radical scavenging abilities of phloretin and its esters.The results showed that the antioxidant and free radical scavenging abilities of phloretin acetylferulic acid esters were stronger than that of phloretin.
Keywords:phloretin  ferulic acid  esterification  antioxidant activity  synthesis
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