Distribution of rhodium in mice submitted to treatment with the adduct of rhodium propionate and sodium isonicotinate |
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| Authors: | de Souza A R Najjar R de Oliveira E Zyngier S B |
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| Affiliation: | 1. Instituto de Química, USP, C.P. 26.077, São Paulo, SP, 05599-970, Brazil.;2. Instituto de Ciências Biomédicas, USP, C.P. 66.208, São Paulo, SP, 05383-970, Brazil, |
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| Abstract: | The distribution of rhodium in Balb/c mice following intraperitoneal (ip) administration of a solution of adduct of rhodium propionate and sodium isonicotinate has been investigated. The metal concentration was determined in blood and in the following organ tissues: brain, heart, lung, liver, spleen, kidney, testes, and uterus/ovary, and the rhodium concentration was obtained by Inductively Coupled Argon Atomic Emission Spectroscopy (ICP-AES). The metal was detected in all organ tissues examined, mainly in spleen, liver, uterus/ovary and heart. Nine days after the injection, traces of rhodium were found in the liver and kidneys and, twenty days after the injection, only in the liver. |
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