| 大豆胚轴中异黄酮的提取及其抗血小板聚集作用的研究 |
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| 引用本文： | 全吉淑,尹学哲,工藤重光.大豆胚轴中异黄酮的提取及其抗血小板聚集作用的研究[J].食品研究与开发,2006,27(10):57-59. |
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| 作者姓名： | 全吉淑 尹学哲 工藤重光 |
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| 作者单位： | 1. 延边大学医学院,吉林,延吉,133000
2. 日本东北食效科学研究所,日本,青森,030-0842 |
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| 摘 要： | 从大豆胚轴提取总糖苷后，采用C18反相柱层析法分离大豆异黄酮糖苷，再将其水解制备成异黄酮苷元，并研究大豆异黄酮对人血小板聚集性的影响。结果：在体外人血小板聚集实验中，大豆异黄酮苷元均抑制ADP、胶原蛋白和肾上腺素诱导的血小板聚集。提示：大豆异黄酮可能有助于防止血栓形成。
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| 关 键 词： | 大豆胚轴 异黄酮 血小板聚集 |
| 收稿时间： | 2006-07-15 |
| 修稿时间： | 2006年7月15日 |
EXTRACTION OF ISOFLAVONES FROM SOYBEAN HYPOCOTYL AND THEIR ANTI-PLATLET AGGREGATIVE EFFECT |
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| QUAN Ji-shu,YIN Xue-zhe,Kudou Shigemitsu.EXTRACTION OF ISOFLAVONES FROM SOYBEAN HYPOCOTYL AND THEIR ANTI-PLATLET AGGREGATIVE EFFECT[J].Food Research and Developent,2006,27(10):57-59. |
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| Authors: | QUAN Ji-shu YIN Xue-zhe Kudou Shigemitsu |
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| Affiliation: | 1. Medical College Yanbian University, Yanji 133000, Jilin, China; 2.Institute of Food Factors Science for Health, Aomori 030-0842, Aomori, Japan |
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| Abstract: | Total glycosides were extracted from soybean hypocotyl, then isoflavone glycosides were isolated with C18 reversed phase column chromatography. Finally isoflavone aglycones were prepared by hydrolysis of isoflavone glycosides and their influence on aggregation of human platelets were studied. It was resulted that isoflavone aglycones inhibited human platelet aggregation induced by ADP, collagen and epinephrine. The results suggest soybean isoflavones may be useful for the prevention of thrombus formation. |
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| Keywords: | soybean hypocotyl isoflavones platelet aggregation |
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