围术期输血对根治术后膀胱癌患者预后的影响

目的 探讨围术期输血对根治术后膀胱癌患者预后的影响.方法 回顾性分析139例行膀胱癌根治术的患者的临床资料,其中输血组118例和未输血组21例,比较两组患者的总生存期、术后肿瘤复发率、术区淋巴结有无肿大和有无其他脏器转移情况.结果 输血组术后术区淋巴结肿大、其他器官转移及尿路上皮肿瘤复发者比例均高于未输血组(P<0.05);未输血组中位生存期(118个月)高于输血组(21个月)(P<0.05).结论 围术期输血可影响膀胱癌患者的复发率及生存期,需要权衡围术期输血的利弊.

Effect of perioperative blood transfusion on prognosis of patients with bladder cancer after radical resection

Objective To investigate the effect of perioperative blood transfusion on the prognosis of patients with bladder cancer after radical resection.Methods Clinical data of 139 patients with bladder cancer who underwent radical resection were retrospectively analyzed,including 118 cases in the blood transfusion group and 21 cases in non-blood transfusion group.The overall survival time,postoperative tumor recurrence rate,postoperative lymphadenectasis of surgical area and other organs metastasis were compared between the two groups.Results The proportions of the patients with postoperative lymphadenectasis of surgical area,other organs metastasis and recurrence of urothelial tumors in the blood transfusion group were higher than those in the non-blood transfusion group(P<0.05).The survival time of the non-blood transfusion group was longer than that of the blood transfusion group(118 months vs.21 months;P<0.05).Conclusion For patients with bladder cancer,perioperative blood transfusion can affect the recurrence rate and survival time,thereby it is necessary to weigh the pros and cons of perioperative blood transfusion.