磁共振改良DIXON定量技术在椎体转移瘤中的诊断价值

目的 探讨磁共振改良DIXON定量技术（mDIXON Quant）在椎体转移瘤中的诊断价值。方法 回顾性分析152例经病理确诊为恶性肿瘤并椎体转移患者的MRI图像。扫描序列包括T1WI、STIR、mDIXON Quant及T1WI压脂增强。分析T1WI、FF图像在椎体转移瘤中的诊断效能；比较正常椎体与椎体转移瘤FF值的差异，应用ROC曲线评估FF值的诊断效能。结果 FF图像诊断椎体转移瘤的敏感度、假阳性率、假阴性率、阴性预测值、准确性均高于T1WI。椎体转移瘤的FF值明显低于正常椎体（Z=-21.792, P<0.05），其中ROC曲线下面积为0.987，截断值为9.87%，诊断敏感度99.6%，特异性92.0%。结论 mDIXON Quant能够定量测定椎体转移瘤的脂肪含量，对椎体转移瘤的诊断具有较高的诊断效能。

Diagnostic Value of mDIXON Quant MRI for Vertebral Metastasis

Objective To evaluate the diagnostic efficacy of mDIXON Quant for vertebral metastasis. Methods We retrospectively analyzed MRI images of 152 patients with clinically diagnosed malignant tumors and vertebral metastases. Scanning sequence included T1WI, STIR, mDIXON Quant and enhanced T1WI. We compared the diagnostic efficiency between T1WI and FF images for vertebral metastases. FF values between normal vertebral body and vertebral metastases were quantitatively compared, and the diagnostic efficacy of FF value was evaluated by ROC curve. Results The sensitivity, false positive rate, false negative rate, negative predictive value and accuracy of FF images in the diagnosis of vertebral metastases were all higher than those of T1WI images. The FF value of vertebral metastasis was significantly lower than that of normal vertebral body (Z=-21.792, P<0.05), and the area under ROC curve was 0.987 and the cutoff value was 9.87%. The diagnostic sensitivity and specificity of vertebral metastasis were 99.6% and 92.0%. Conclusion mDIXON Quant can quantitatively determine the fat content of vertebral metastasis and has a high diagnostic efficiency for vertebral metastases.