出血性溃疡危险因素分析

目的 :通过分析消化性溃疡并发上消化道出血的病人 ,找出危险因素以指导此合并症的预防。方法 :胃溃疡 (GU)40例 (其中出血亚群21例 ,无出血亚群19例 )、十二指肠球部溃疡 (DU)70例 (其中出血亚群38例 ,无出血亚群32例 )共110例 ,对其13个临床特征及内镜所见变量 ,按统一表格逐一进行询问与记录。GU及DU各自的出血亚群与无出血亚群各个变量间的差异用x2检验 ,求其优势比 (O.R.)及其95%可信限。结果 :年龄55岁以上、吸烟、饮酒及溃疡直径≥1cm的胃溃疡出血危险性显著增加 (P<0.05) ;年龄24岁以下 ,病程3年以上的十二指肠球部溃疡出血危险性显著升高 (P<0.05)。结论 :首症年龄、吸烟、饮酒及溃疡直径是GU出血的危险因素 ;年龄、病程是DU出血的危险因素

Analysis on risk factors of peptic ulcer bleeding

Objective:To prevent peptic ulcer bleeding by analyzing its risk factors. Methods:Thirteen clinical and endoscopic variables were investigated. The difference between bleeding subgroups and no bleeding subgroups of gastric ulcer(GU)and duodenal ulcer(DU)were analyzed by X test. Odds ratio(O.R.)and 95%confidence interval(C.I.)were calculated. Results:Bleeding risks rose in GU patients who were above 55 years, smoking and ingestion of alcohol and whose ulcer size >or=1cm in diameter, so did DU patients who were below 24 and its course was longer than 3 years. Conclusion:Age,smoking,drinking and ulcers size are the risk factors of GU, while age and course are duodenal ulcer s risk factors.