| 用模型分析心肌血流与阻力的灌注压依赖性 |
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| 引用本文： | 刘琼,郑振声,吴云鹏,蔡绍皙.用模型分析心肌血流与阻力的灌注压依赖性[J].生物医学工程研究,1995(Z1). |
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| 作者姓名： | 刘琼 郑振声 吴云鹏 蔡绍皙 |
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| 作者单位： | 中山医科大学辅助循环实验室，重庆大学生物工程研究院 |
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| 基金项目： | 中山医科大学卫生部辅助循环重点实验室自然科学基金 |
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| 摘 要： | 合理考虑心肌内有代表性的血管网，选用实测主动脉压和左心室腔压作为输入数据，建立了一种适于研究左心室壁心肌血流动力学机制的模型，能够同时仿真冠脉系统的动、静脉及微循环血流。在预测心肌灌注时相分布接近现有结论的基础上，研究了心肌血流与血管床阻力的灌注压依赖性。结论有助于理解主动脉内气囊反搏和体外反搏的治疗机制。
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| 关 键 词： | 数学模型，冠状循环，血流动力学，主动脉内气囊反搏，体外反搏 |
MODEL-BASED STUDY OF TIME-DEPENDENT CORONARY BLOOD FLOW DISTRIBUTION IN LEFT VENTRICULAR WALL AND ITS DEPENDENCES ON CORONARY PRESSURE DRIVING FORCE |
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| Liu Qiong, Zheng Zhensheng, Wu Yunpeng, Cai Shaoxi.MODEL-BASED STUDY OF TIME-DEPENDENT CORONARY BLOOD FLOW DISTRIBUTION IN LEFT VENTRICULAR WALL AND ITS DEPENDENCES ON CORONARY PRESSURE DRIVING FORCE[J].Journal Of Blomedical Englneerlng Research,1995(Z1). |
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| Authors: | Liu Qiong Zheng Zhensheng Wu Yunpeng Cai Shaoxi |
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| Abstract: | The proposed model is beneficial to understanding mechanism of in-tramyocardial circulation. Not only the coronary arteries but also veins blood flow can beemulated by the model which represents the typical vessel nets completely. The experimen-tally measured timed-varying perfusion and left ventricular pressure sources are used asdriving inputs for the emulation. The phasic coronary blood flow characteristics predicted bythe model exhibit waveform patterns that correlate qualitatively with those generally accept-ed results. In addition, more work is made about the mvocardial infusion and resistanceswhich are essentially controlled by the coronary pressure driving force.The results make itclear that the LABP and ECP are conduced to balance between supply and demand of coro-nary blood flow. |
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| Keywords: | Mathematical model Coronary circulation Blood dynamics IABP(Intra-aortic balloon pumping ECP (External counterpulsation) |
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