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| 阿托伐他汀对急性脑梗死患者血清超敏C反应蛋白及一氧化氮水平的影响 | |
| 引用本文： | 刘伟民,杨晓武,周红兵,刘廷筑,余红岚.阿托伐他汀对急性脑梗死患者血清超敏C反应蛋白及一氧化氮水平的影响[J].临床神经病学杂志,2009,22(1). |
| 作者姓名： | 刘伟民 杨晓武 周红兵 刘廷筑 余红岚 |
| 作者单位： | 1. 贵阳市第一人民医院神经内科,550002 2. 贵阳市第一人民医院心内科,550002 3. 贵阳市第一人民医院检验科,550002 |
| 摘 要： | 目的研究阿托伐他汀对急性脑梗死(ACI)患者血清超敏C反应蛋白(hs-CRP)及一氧化氮(NO)水平的影响。方法将60例ACI患者随机分为阿托伐他汀组(30例)和常规治疗组(30例)。阿托伐他汀组在常规治疗基础上加用阿托伐他汀20mg,每日1次,连续服用14d。在治疗前后检测血清hs-CRP和NO含量,并进行神经功能缺损程度评分(NDS)评定。结果治疗14d时两组血清hs-CRP水平均较治疗前明显下降(均P<0.01),且阿托伐他汀组较常规治疗组下降明显(P<0.01);两组血清NO水平较治疗前明显升高(均P<0.01),且阿托伐他汀组较常规治疗组升高明显(P<0.05);两组NDS评分较治疗前明显下降(均P<0.01),且阿托伐他汀组较常规治疗组下降明显(P<0.05)。结论阿托伐他汀能明显降低ACI患者血清hs-CRP水平,升高NO水平;有助于ACI患者的神经功能恢复。 |
| 关 键 词： | 阿托伐他汀 脑梗死 超敏C反应蛋白 一氧化氮 |
Effect of Atorvastatin on the level of serum high-sensitivity C-reactive protein and nitric oxide in patients with acute cerebral infarction |
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| LIU Wei-min,YANG Xiao-wu,ZHOU Hong-bing,et al..Effect of Atorvastatin on the level of serum high-sensitivity C-reactive protein and nitric oxide in patients with acute cerebral infarction[J].Journal of Clinical Neurology,2009,22(1). | |
| Authors: | LIU Wei-min YANG Xiao-wu ZHOU Hong-bing |
| Affiliation: | LIU Wei-min,YANG Xiao-wu,ZHOU Hong-bing,et al. Department of Neurology,the First People's Hospital of Guiyang,Guiyang 550002,China |
| Abstract: | Objective To study the effect of Atorvastatin on the level of serum high-sensitivity C-reactive protein(hs-CRP) and nitric oxide(NO) in patients with acute cerebral infartion(ACI). Methods 60 patients with ACI were randomly divided into the Atorvastatin therapy group (n=30) and the conventional therapy group (n=30). At the basic of conventional therapy, the Atorvastatin therapy group was treated with Atorvastatin 20 mg/d. Both groups were treated for 14 consecutive days. The levels of serum hs-CRP and NO we... |
| Keywords: | Atorvastatin cerebral infarction high-sensitivity C-reactive protein nitric oxide |
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