联合检测肿瘤标记物在肺癌中的临床意义

目的 探讨血清CEA、CA19-9、CA125、CYFRA21-1、TSGF、NSE的联合检测在肺癌的临床诊断、病理分型、肿瘤分期中的临床意义.方法 联合检测122例原发性肺癌完全切除的患者肿瘤标记物的水平.结果 CEA在腺癌中升高较其他明显,CYFRA21-1在鳞癌及腺鳞癌中升高较其他明显,NSE在小细胞癌中升高较其他明显.联合检测在鳞癌敏感性最高,细支气管肺泡癌敏感性最低.结论 血清CEA、CA19-9、CA125、CYFRA21-1、TSGF、NSE的联合检测在肺癌的临床诊断、病理分型、肿瘤分期中具有一定意义.

Clinical significance of combined detection tumor markers in patients with lung cancer

Objective To investigate the clinical significance of CEA,CA19-9,CA125,CYFRA21-1,TSGF,NSE in the clinical diagnosis,pathological classification,and neoplasm staging in lung cancer.Methods To combined detection tumor markers levels in 122 cases of lung cancer underwent pneumonectomy or lobectomy and lymphadenectomy.Results The level of CEA in adenocarcinoma was in significantly higher than that of other pathology types,and the level of CYFRA21-1 in squamous carcinoma and adenosquamous Carcinoma was significantly higher than that of other pathology types,and the level of NSE in small cell lung cancer was significantly higher than that of other pathology types.The sensitivity of combination detection in squamous carcinoma was significantly highest than that of other pathology thpes,and the sensitivity of combination detection in bronchiolo alveolar carcinoma was significantly lowest than that of other pathology thpes.Conclusion Combined detection of serum CEA、CA19-9、CA125、CYFRA21-1、TSGF、NSE has Clinical significance in the clinical diagnosis,pathological classification,neoplasm staging of lung cancer.