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Phase diagram prediction of recycling aqueous two-phase systems formed by a light-sensitive copolymer and dextran
Authors:Zhihua Shao  Fanqi Kong  Xuejun Cao
Affiliation:(1) State Key Laboratory of Bioreactor Engineering, Department of Biochemical Engineering, East China University of Science & Technology, 130 Meilong Rd., Shanghai, 200237, China
Abstract:Our Laboratory has synthesized a novel light-sensitive and recycling copolymer P NBC . The P NBC copolymer could form recycling aqueous two-phase systems with Dextran. Recycling aqueous two-phase systems have important application in bioseparation engineering. Phase diagram prediction of the novel aqueous two-phase systems also is an important aspect in engineering. This article applied the Cabezas model and effective excluded volume (EEV) model to the experimental data of light-sensitive recycling aqueous two-phase systems. It has been found that the EEV model could consist with experimental data very well. The maximum absolute error and average absolute error is 0.81% (wt%) and 0.23% (wt%), respectively.
Keywords:Aqueous Two-phase Systems  Light-sensitive Polymer  Liquid-liquid Equilibria  Thermodynamic Models
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